Pediatric Gastroenterology at Fudan University Children's Hospital Shanghai | CMCS

Expert Digestive & Liver Disease Care for Children at China's Premier Children's Hospital

The Department of Gastroenterology at Fudan University Children's Hospital (FUCH) is one of China's most distinguished pediatric gastroenterology centers, with a national reputation for excellence in the diagnosis and management of inflammatory bowel disease, liver disease, motility disorders, eosinophilic gastrointestinal diseases, and rare digestive conditions in children. The department combines outstanding clinical expertise with a world-class research program and a fully integrated multidisciplinary approach, offering international families access to some of China's most eminent pediatric gastroenterologists and the latest evidence-based treatments for complex childhood digestive and liver diseases.

For international families with a child with Crohn's disease, ulcerative colitis, autoimmune liver disease, a rare digestive condition, or a complex gastrointestinal diagnosis — FUCH's gastroenterology department represents one of the most compelling destinations in Asia. China Medical Concierge Shanghai (CMCS) provides seamless end-to-end coordination for international families throughout their child's care journey at FUCH.

About the Department

FUCH's gastroenterology department is a national key clinical specialty operating dedicated pediatric gastroenterology inpatient wards, a comprehensive outpatient gastroenterology clinic, a pediatric endoscopy suite, a motility laboratory, a liver disease clinic, a nutritional support team, and works in close collaboration with pediatric surgery, radiology, pathology, and genetics through a fully integrated multidisciplinary team.

Faculty members publish regularly in leading pediatric gastroenterology journals including Gastroenterology, Journal of Pediatric Gastroenterology and Nutrition, Inflammatory Bowel Diseases, Hepatology, and Journal of Hepatology.

Conditions Treated

Inflammatory Bowel Disease (IBD)

• Pediatric Crohn's Disease — Exclusive enteral nutrition (EEN) as first-line induction for luminal CD; corticosteroids; azathioprine and 6-mercaptopurine; methotrexate; anti-TNF therapy (infliximab, adalimumab); ustekinumab; vedolizumab; risankizumab; ozanimod; therapeutic drug monitoring (TDM) for biologic optimization; treat-to-target strategy with mucosal healing as goal
• Pediatric Ulcerative Colitis — 5-ASA for mild-moderate UC; corticosteroids for moderate-severe UC; infliximab and adalimumab; vedolizumab; ustekinumab; tofacitinib and upadacitinib for refractory UC; colectomy coordination with pediatric surgery for medically refractory UC
• Very Early Onset IBD (VEO-IBD) — Genetic panel testing for monogenic IBD (IL-10 signaling defects, XIAP, CGD, WAS, and others); targeted therapy based on genetic diagnosis; hematopoietic stem cell transplantation for selected monogenic IBD
• IBD-Related Complications — Stricture dilation; fistula management; perianal disease; growth failure; bone health; IBD-related arthritis and uveitis
• Therapeutic Drug Monitoring (TDM) — Proactive TDM for infliximab and adalimumab; dose optimization based on trough levels and antibody testing

Liver Disease

• Autoimmune Hepatitis (AIH) — Prednisolone + azathioprine induction and maintenance; mycophenolate mofetil for azathioprine-intolerant patients; budesonide for mild AIH; liver transplantation for acute liver failure
• Primary Sclerosing Cholangitis (PSC) — Ursodeoxycholic acid; endoscopic management of dominant strictures; liver transplantation for end-stage PSC; IBD-PSC overlap management
• Wilson's Disease — D-penicillamine and trientine chelation; zinc maintenance therapy; liver transplantation for acute liver failure or decompensated cirrhosis
• Alagille Syndrome — Maralixibat (IBAT inhibitor) for cholestatic pruritus; nutritional support; liver transplantation for end-stage liver disease
• Progressive Familial Intrahepatic Cholestasis (PFIC) — PFIC1/2/3 genetic diagnosis; maralixibat and odevixibat (IBAT inhibitors) for PFIC2; biliary diversion surgery; liver transplantation
• Biliary Atresia — Kasai portoenterostomy coordination with pediatric surgery; liver transplantation for Kasai failure
• Neonatal Cholestasis — Systematic evaluation; TORCH infections; metabolic liver diseases; biliary atresia vs. neonatal hepatitis differentiation
• Non-Alcoholic Fatty Liver Disease (NAFLD/MASLD) — Lifestyle intervention; vitamin E; emerging pharmacotherapy
• Acute Liver Failure — Intensive management; N-acetylcysteine for paracetamol-induced ALF; emergency liver transplantation evaluation
• Metabolic Liver Diseases — Alpha-1 antitrypsin deficiency; glycogen storage diseases; tyrosinemia (nitisinone); galactosemia

Gastrointestinal Motility Disorders

• Gastroparesis — Dietary modification; prokinetics (metoclopramide, domperidone, erythromycin); gastric electrical stimulation
• Functional Dyspepsia — Acid suppression; prokinetics; tricyclic antidepressants; psychological support
• Irritable Bowel Syndrome (IBS) — Dietary modification (low FODMAP); antispasmodics; gut-directed hypnotherapy; psychological support
• Chronic Intestinal Pseudo-Obstruction (CIPO) — Nutritional support; prokinetics; neostigmine; surgical decompression
• Hirschsprung's Disease (Post-operative) — Management of Hirschsprung-associated enterocolitis; constipation and soiling after pull-through surgery
• Anorectal Malformations (Post-operative) — Bowel management programs; biofeedback

Eosinophilic Gastrointestinal Diseases

• Eosinophilic Esophagitis (EoE) — Proton pump inhibitors; swallowed topical corticosteroids (fluticasone, budesonide); elimination diets (6-food, 4-food, 2-food); dupilumab for refractory EoE; esophageal dilation for strictures
• Eosinophilic Gastroenteritis — Elimination diets; corticosteroids; montelukast

Celiac Disease & Malabsorption

• Celiac Disease — Strict gluten-free diet; nutritional deficiency correction; refractory celiac disease management
• Short Bowel Syndrome — Parenteral nutrition; teduglutide (GLP-2 analogue) for intestinal rehabilitation; intestinal transplantation evaluation
• Congenital Diarrheal Disorders — Microvillus inclusion disease; tufting enteropathy; genetic diagnosis; parenteral nutrition; intestinal transplantation

Gastrointestinal Infections & Other Conditions

• Helicobacter pylori — Clarithromycin-based and bismuth quadruple therapy; culture-guided therapy for resistant H. pylori
• Clostridioides difficile Infection — Vancomycin and fidaxomicin; fecal microbiota transplantation (FMT) for recurrent CDI
• Gastrointestinal Polyps — Juvenile polyposis syndrome; Peutz-Jeghers syndrome; familial adenomatous polyposis; endoscopic polypectomy and surveillance
• Gastrointestinal Bleeding — Endoscopic evaluation and hemostasis; capsule endoscopy for obscure GI bleeding
• Pancreatitis — Acute and chronic pancreatitis; PRSS1 and SPINK1 mutation testing; ERCP for pancreatic duct stones and strictures

Pediatric Endoscopy Program

FUCH's pediatric endoscopy program is one of the most experienced in China, offering the full range of diagnostic and therapeutic endoscopic procedures for children of all ages:

• Upper GI Endoscopy (EGD) — Diagnostic and therapeutic; foreign body removal; esophageal dilation; PEG tube placement
• Colonoscopy — Diagnostic and therapeutic; polypectomy; mucosal biopsy for IBD assessment
• Capsule Endoscopy — For small bowel evaluation in Crohn's disease and obscure GI bleeding
• Device-Assisted Enteroscopy — Single and double balloon enteroscopy for small bowel lesions
• ERCP — For biliary and pancreatic duct pathology; stone extraction; stricture dilation
• Endoscopic Ultrasound (EUS) — For pancreatic and biliary evaluation

Nutritional Support Program

Nutrition is central to pediatric gastroenterology care. FUCH's nutritional support program provides:

• Exclusive enteral nutrition (EEN) as primary therapy for pediatric Crohn's disease
• Elemental and semi-elemental formulas for food allergy and malabsorption
• Parenteral nutrition for short bowel syndrome and intestinal failure
• Teduglutide for intestinal rehabilitation in short bowel syndrome
• Dietitian-led nutritional assessment and counseling

Why International Families Choose FUCH Gastroenterology

• IBD Expertise — Comprehensive biologic therapy program with TDM-guided optimization; VEO-IBD genetic diagnosis and targeted therapy
• Liver Disease Leadership — Maralixibat and odevixibat for PFIC and Alagille syndrome; Wilson's disease and autoimmune hepatitis expertise
• Eosinophilic Esophagitis — Dupilumab and elimination diet programs for EoE
• Pediatric Endoscopy — Full range of diagnostic and therapeutic endoscopy for children of all ages
• Nutritional Support — EEN, parenteral nutrition, and teduglutide for intestinal failure
• Cost-Effectiveness — World-class pediatric gastroenterology care at significantly lower cost than equivalent treatment in Western countries

The CMCS Patient Journey

1. Initial Inquiry — Share your child's GI history, endoscopy reports, biopsy results, imaging, genetic testing, and current medications with CMCS.
2. Medical Record Preparation — We translate and organize your child's records for specialist pre-consultation review.
3. Specialist Matching — We identify the most appropriate pediatric gastroenterologist based on your child's condition — IBD, liver disease, motility disorder, EoE, or rare GI condition.
4. Priority Scheduling — We secure a consultation with minimal waiting time.
5. Travel & Logistics — Assistance with visa invitation letters, family accommodation near FUCH, and Shanghai airport transfers.
6. On-Site Concierge — Bilingual coordinators accompany your family throughout hospital visits, managing registration, translation, and communication.
7. Diagnostic Support — Full coordination of endoscopy, liver biopsy, motility studies, genetic testing, and other required investigations.
8. Post-Consultation Follow-Up — Biopsy and test result translation, treatment plan interpretation, and remote follow-up coordination after you return home.

Book a Consultation

If your child has Crohn's disease, ulcerative colitis, liver disease, eosinophilic esophagitis, a motility disorder, or a rare digestive condition — CMCS can arrange a specialist consultation with FUCH's pediatric gastroenterology team in Shanghai.

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