Rhinology & Endoscopic Sinus Surgery at Fudan University Eye & ENT Hospital Shanghai | CMCS

Expert Nasal & Sinus Care at China's Premier ENT Specialty Hospital

The Department of Rhinology at Fudan University Eye & ENT Hospital (EENT Hospital) is one of China's most distinguished rhinology centers, with a national reputation for excellence in functional endoscopic sinus surgery (FESS), chronic rhinosinusitis with nasal polyps, eosinophilic chronic rhinosinusitis, skull base surgery via the endoscopic endonasal approach, olfactory disorders, and the management of complex nasal and sinus conditions. As China's only dedicated eye and ENT specialty hospital at the tertiary level, EENT Hospital's rhinology department combines outstanding surgical expertise with a world-class research program, offering international patients access to some of China's most eminent rhinologists and endoscopic skull base surgeons.

For international patients with chronic rhinosinusitis, nasal polyps, refractory sinusitis, olfactory loss, or a complex nasal or sinus condition — EENT Hospital's rhinology department offers an unparalleled combination of medical and surgical expertise, endoscopic capability, and research leadership. China Medical Concierge Shanghai (CMCS) provides seamless end-to-end coordination for international patients throughout their rhinological care journey at EENT Hospital.

About the Department

EENT Hospital's rhinology department is a national key clinical specialty operating a comprehensive rhinology clinic, a nasal endoscopy suite, a sinus CT analysis service, an olfactory testing laboratory, a biologic therapy clinic for severe chronic rhinosinusitis, an endoscopic skull base surgery program in collaboration with neurosurgery, and works in close collaboration with allergy and immunology, pulmonology, and neurosurgery through a fully integrated multidisciplinary team.

Faculty members publish regularly in leading rhinology journals including Journal of Allergy and Clinical Immunology, Rhinology, International Forum of Allergy & Rhinology, Laryngoscope, and American Journal of Rhinology & Allergy.

Conditions Treated

Chronic Rhinosinusitis (CRS)

• CRS without Nasal Polyps (CRSsNP) — Nasal saline irrigation; intranasal corticosteroids; short-course oral corticosteroids; culture-directed antibiotic therapy; FESS for medically refractory CRSsNP; balloon sinuplasty for selected patients
• CRS with Nasal Polyps (CRSwNP) — Intranasal corticosteroids; short-course oral corticosteroids; saline irrigation; FESS for polyp removal and sinus drainage; biologic therapy for severe/refractory CRSwNP
• Eosinophilic CRS (eCRS) — High tissue eosinophil count; high recurrence after surgery; biologic therapy (dupilumab, mepolizumab, benralizumab, omalizumab) for eosinophilic CRSwNP; one of China's most experienced eCRS biologic programs
• Allergic Fungal Rhinosinusitis (AFRS) — FESS with complete mucin removal; oral corticosteroids; antifungal therapy; allergen immunotherapy; high recurrence monitoring
• Aspirin-Exacerbated Respiratory Disease (AERD / Samter's Triad) — FESS; aspirin desensitization; dupilumab; montelukast; zileuton

Biologic Therapy for Severe CRSwNP

EENT Hospital's biologic therapy program for severe chronic rhinosinusitis with nasal polyps is one of the most experienced in China:

• Dupilumab (Dupixent) — Anti-IL-4Rα (blocks IL-4 and IL-13); approved for severe CRSwNP; significant polyp reduction and symptom improvement; also treats comorbid asthma and atopic dermatitis; SINUS-24 and SINUS-52 trial evidence
• Mepolizumab (Nucala) — Anti-IL-5; for severe eosinophilic CRSwNP; reduces polyp recurrence after surgery
• Benralizumab (Fasenra) — Anti-IL-5Rα; for severe eosinophilic CRSwNP with comorbid severe eosinophilic asthma
• Omalizumab (Xolair) — Anti-IgE; for CRSwNP with comorbid allergic asthma; POLYP 1 and POLYP 2 trial evidence
• Tezepelumab (Tezspire) — Anti-TSLP; for severe CRSwNP with comorbid severe asthma
• Patient Selection — Biologic selection based on biomarkers (blood eosinophils, total IgE, FeNO), comorbidities, and prior treatment response

Functional Endoscopic Sinus Surgery (FESS)

• Standard FESS — Uncinectomy; maxillary antrostomy; anterior and posterior ethmoidectomy; sphenoidotomy; frontal sinusotomy (Draf I, IIa, IIb, III); image-guided surgery (IGS) for complex anatomy and revision cases
• Extended FESS — Draf III (modified Lothrop) frontal sinusotomy for frontal sinus disease; medial maxillectomy for inverted papilloma; total ethmoidectomy
• Balloon Sinuplasty — Office-based balloon dilation of maxillary, frontal, and sphenoid ostia for selected patients with mild-moderate CRS; no tissue removal; rapid recovery
• Revision FESS — For recurrent CRS after prior surgery; scar tissue removal; neo-ostium revision; image-guided navigation
• Image-Guided Surgery (IGS) — Electromagnetic and optical navigation for complex revision cases, frontal sinus surgery, and skull base proximity; real-time anatomical confirmation

Nasal Septal & Structural Disorders

• Deviated Nasal Septum — Septoplasty; endoscopic septoplasty; combined septorhinoplasty for functional and aesthetic correction
• Turbinate Hypertrophy — Inferior turbinate reduction (submucosal resection, radiofrequency, microdebrider); middle turbinate concha bullosa resection
• Nasal Valve Collapse — Spreader grafts; alar batten grafts; functional rhinoplasty
• Empty Nose Syndrome — Nasal humidification; saline irrigation; submucosal implants for turbinate augmentation

Olfactory Disorders

EENT Hospital's olfactory clinic is one of China's most specialized, offering comprehensive evaluation and treatment for smell disorders:

• Post-Viral Olfactory Loss — Including post-COVID-19 anosmia/parosmia; olfactory training (structured smell training with four odors); systemic and topical corticosteroids; omega-3 supplementation; sodium citrate nasal spray; PRP (platelet-rich plasma) nasal instillation; theophylline
• Sinonasal Olfactory Loss — Treatment of underlying CRS/polyps; FESS; corticosteroids
• Post-Traumatic Olfactory Loss — Olfactory training; corticosteroids; spontaneous recovery monitoring
• Olfactory Testing — Sniffin' Sticks test (threshold, discrimination, identification — TDI score); University of Pennsylvania Smell Identification Test (UPSIT); olfactory MRI for olfactory bulb volume assessment

Sinonasal Tumors

• Inverted Papilloma — Endoscopic medial maxillectomy; Draf III for frontal sinus involvement; recurrence surveillance; HPV testing
• Sinonasal Malignancies — Squamous cell carcinoma; adenocarcinoma; olfactory neuroblastoma (esthesioneuroblastoma); sinonasal undifferentiated carcinoma (SNUC); NUT carcinoma; endoscopic and open resection; coordination with oncology and radiation oncology
• Juvenile Nasopharyngeal Angiofibroma (JNA) — Preoperative embolization; endoscopic resection; open approaches for extensive disease
• Fibrous Dysplasia — Surgical decompression for optic nerve or orbital involvement; bisphosphonates

Endoscopic Skull Base Surgery

EENT Hospital's endoscopic skull base surgery program is one of China's most experienced, offering minimally invasive endonasal approaches to the anterior and central skull base in collaboration with neurosurgery:

• Pituitary Adenoma — Endoscopic endonasal transsphenoidal surgery (EETS); extended approaches for suprasellar and parasellar extension; collaboration with neurosurgery and endocrinology
• Craniopharyngioma — Endoscopic endonasal approach for selected cases; collaboration with neurosurgery
• CSF Leak Repair — Endoscopic repair of anterior skull base CSF leaks; multilayer closure with fat, fascia, and mucosal flaps; nasoseptal flap (Hadad-Bassagaisteguy flap)
• Meningoencephalocele — Endoscopic endonasal repair; collaboration with neurosurgery
• Orbital Decompression — Endoscopic medial and inferior orbital wall decompression for thyroid eye disease (Graves' ophthalmopathy); coordination with ophthalmology
• Optic Nerve Decompression — Endoscopic optic canal decompression for traumatic optic neuropathy and fibrous dysplasia
• Dacryocystorhinostomy (DCR) — Endoscopic DCR for nasolacrimal duct obstruction; coordination with ophthalmology

Allergic Rhinitis

• Allergic Rhinitis — Allergen avoidance; intranasal corticosteroids; antihistamines; leukotriene receptor antagonists; allergen immunotherapy (subcutaneous and sublingual); dupilumab for severe allergic rhinitis with comorbid asthma
• Sublingual Immunotherapy (SLIT) — House dust mite SLIT (Acarizax); grass pollen SLIT; 3-year course for long-term tolerance

Why International Patients Choose EENT Hospital Rhinology

• Biologic Therapy Leadership — One of China's most experienced centers for dupilumab, mepolizumab, and omalizumab for severe CRSwNP
• Olfactory Disorder Expertise — Specialized post-COVID olfactory loss program; structured olfactory training; PRP nasal instillation
• Endoscopic Skull Base Surgery — Pituitary adenoma, CSF leak repair, and orbital decompression via minimally invasive endonasal approach
• Draf III Frontal Sinusotomy — Expert modified Lothrop procedure for refractory frontal sinus disease
• AERD / Samter's Triad — Aspirin desensitization and dupilumab for aspirin-exacerbated respiratory disease
• Cost-Effectiveness — World-class rhinological care at significantly lower cost than equivalent treatment in Western countries

The CMCS Patient Journey

1. Initial Inquiry — Share your nasal/sinus history, CT sinus scans, nasal endoscopy reports, allergy testing, and current medications with CMCS.
2. Medical Record Preparation — We translate and organize your records for specialist pre-consultation review.
3. Specialist Matching — We identify the most appropriate rhinologist based on your condition — CRS, nasal polyps, olfactory loss, sinonasal tumor, or skull base surgery.
4. Priority Scheduling — We secure a consultation with minimal waiting time.
5. Travel & Logistics — Assistance with visa invitation letters, accommodation near EENT Hospital, and Shanghai airport transfers.
6. Diagnostic Assessment — Full coordination of nasal endoscopy, CT sinus, olfactory testing, allergy testing, and other required investigations.
7. Treatment Coordination — Full coordination of biologic therapy initiation, FESS surgical admission, or skull base surgery.
8. Post-Treatment Follow-Up — Treatment report translation, biologic injection schedule guidance, and remote follow-up coordination after you return home.

Book a Consultation

If you have chronic rhinosinusitis, nasal polyps, olfactory loss, a sinonasal tumor, or require endoscopic sinus or skull base surgery — CMCS can arrange a specialist consultation with EENT Hospital's rhinology team in Shanghai.

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