Respiratory Medicine at Huadong Hospital Shanghai | CMCS

Expert Respiratory Care at One of Shanghai's Most Prestigious Academic Medical Centers

The Department of Respiratory Medicine at Huadong Hospital — affiliated with Fudan University — is one of Shanghai's most distinguished respiratory medicine centers, with a national reputation for excellence in COPD, interstitial lung disease, sleep-disordered breathing, lung cancer diagnosis, respiratory infections, and the management of complex respiratory conditions in older adults. As one of Shanghai's most prestigious hospitals with a long tradition of serving senior patients, Huadong Hospital's respiratory medicine department offers particular expertise in age-related respiratory conditions — COPD, interstitial lung disease, sleep apnea, and respiratory complications of systemic disease — uniquely integrated with the hospital's world-class geriatric medicine and clinical nutrition programs. China Medical Concierge Shanghai (CMCS) provides seamless end-to-end coordination for international patients throughout their respiratory care journey at Huadong Hospital.

About the Department

The respiratory medicine department is a national key clinical specialty operating dedicated respiratory inpatient wards, a respiratory intensive care unit (RICU), a pulmonary function laboratory, a bronchoscopy suite, a sleep medicine laboratory, an interstitial lung disease clinic, a COPD management clinic, an asthma clinic, a lung cancer diagnostic clinic, and works in close collaboration with geriatric medicine, oncology, clinical nutrition, thoracic surgery, and critical care through a fully integrated multidisciplinary team.

Conditions Treated

COPD & Emphysema

• COPD Assessment — Spirometry; GOLD staging; CAT score; mMRC dyspnea scale; 6-minute walk test; CT chest for emphysema phenotyping; exacerbation history; comorbidity assessment
• Inhaler Therapy — LAMA (tiotropium, umeclidinium, glycopyrronium, aclidinium); LABA (salmeterol, formoterol, indacaterol, olodaterol, vilanterol); LAMA+LABA combinations; ICS+LABA+LAMA triple therapy; Trelegy Ellipta; Breztri Aerosphere
• Biologic Therapy — Dupilumab for COPD with type 2 inflammation (eosinophil ≥300); itepekimab (anti-IL-33) for COPD; tezepelumab for COPD with type 2 inflammation
• Acute Exacerbation Management — Systemic corticosteroids; antibiotics; bronchodilators; NIV (BiPAP) for hypercapnic respiratory failure; high-flow nasal oxygen (HFNO); ICU coordination
• Pulmonary Rehabilitation — Exercise training; breathing techniques; education; nutritional support coordination; coordination with rehabilitation medicine
• Bronchoscopic Lung Volume Reduction — Endobronchial valves (Zephyr) for severe emphysema with intact fissures; coils; thermal vapor ablation; coordination with thoracic surgery for surgical LVRS
• COPD in Older Adults — Frailty-adjusted management; inhaler device selection for elderly; nutritional optimization; coordination with geriatric medicine

Asthma

• Mild-Moderate Asthma — ICS; ICS+LABA; SABA reliever; SMART therapy (budesonide/formoterol as maintenance and reliever)
• Severe Asthma — Biologic therapy: mepolizumab (anti-IL-5) for eosinophilic asthma; benralizumab; dupilumab (anti-IL-4/13) for type 2 asthma; tezepelumab (anti-TSLP) for severe uncontrolled asthma regardless of phenotype; omalizumab for allergic asthma; itepekimab
• Bronchial Thermoplasty — For severe persistent asthma not controlled with biologics; bronchoscopic procedure; smooth muscle reduction
• Asthma-COPD Overlap (ACO) — ICS-containing regimens; biologic therapy for type 2 inflammation

Interstitial Lung Disease (ILD)

• Idiopathic Pulmonary Fibrosis (IPF) — Nintedanib (Ofev); pirfenidone (Esbriet); inhaled treprostinil for IPF with PH; sildenafil for IPF-PH; lung transplantation evaluation; oxygen therapy; pulmonary rehabilitation
• Progressive Pulmonary Fibrosis (PPF) — Nintedanib for non-IPF progressive fibrotic ILD (INBUILD trial); systemic sclerosis-ILD; RA-ILD; NSIP
• Hypersensitivity Pneumonitis (HP) — Antigen avoidance; corticosteroids; mycophenolate; azathioprine; nintedanib for fibrotic HP
• Connective Tissue Disease-ILD — SSc-ILD: nintedanib; tocilizumab; rituximab; cyclophosphamide; mycophenolate; PM/DM-ILD: corticosteroids + immunosuppression; RA-ILD: nintedanib; abatacept
• Sarcoidosis — Corticosteroids; methotrexate; azathioprine; hydroxychloroquine; infliximab for refractory sarcoidosis
• Bronchoscopic Diagnosis — BAL; transbronchial biopsy; cryobiopsy for ILD diagnosis; EBUS-TBNA for mediastinal lymphadenopathy

Sleep-Disordered Breathing

• Obstructive Sleep Apnea (OSA) — Polysomnography; home sleep testing; CPAP; auto-CPAP; BiPAP; mandibular advancement device; hypoglossal nerve stimulation (Inspire) coordination with ENT; positional therapy; weight management
• Central Sleep Apnea (CSA) — Treatment of underlying cause (heart failure, opioids); adaptive servo-ventilation (ASV) for non-hypercapnic CSA; BiPAP-ST for hypercapnic CSA
• Obesity Hypoventilation Syndrome (OHS) — NIV (BiPAP); weight loss; bariatric surgery coordination
• Sleep Apnea in Older Adults — High prevalence in elderly; CPAP adherence strategies for older patients; cognitive impact of untreated OSA; coordination with geriatric medicine and neurology
• Insomnia — CBT-I; sleep hygiene; melatonin; low-dose doxepin; lemborexant; daridorexant (dual orexin receptor antagonist)

Respiratory Infections

• Community-Acquired Pneumonia (CAP) — PSI/CURB-65 severity assessment; beta-lactam + macrolide; respiratory fluoroquinolone; ICU-level care for severe CAP; Legionella and pneumococcal urinary antigen testing
• Hospital-Acquired & Ventilator-Associated Pneumonia — Culture-directed antibiotics; anti-MRSA therapy (vancomycin, linezolid, ceftaroline); anti-Pseudomonal coverage; cefiderocol for MDR gram-negative
• Tuberculosis — Standard RHEZ regimen; drug-resistant TB (MDR-TB, XDR-TB); bedaquiline; delamanid; pretomanid; linezolid; coordination with public health
• Fungal Infections — Aspergillosis: voriconazole; isavuconazole; liposomal amphotericin B; Pneumocystis jirovecii pneumonia (PCP): TMP-SMX; atovaquone; Cryptococcus: fluconazole; amphotericin B + flucytosine
• Post-COVID Respiratory Complications — Post-COVID ILD; pulmonary fibrosis; exercise intolerance; breathlessness; pulmonary rehabilitation; coordination with rehabilitation medicine

Pulmonary Vascular Disease

• Pulmonary Arterial Hypertension (PAH) — ERA + PDE5i + prostacyclin combination; sotatercept (Winrevair) for PAH; selexipag; IV epoprostenol; inhaled treprostinil; riociguat for CTEPH
• Pulmonary Embolism (PE) — Anticoagulation (DOACs); systemic thrombolysis for massive PE; catheter-directed thrombolysis; IVC filter; CTEPH evaluation

Bronchoscopy & Interventional Pulmonology

• Diagnostic Bronchoscopy — BAL; transbronchial biopsy; cryobiopsy; EBUS-TBNA for mediastinal staging; radial EBUS for peripheral lesions; navigational bronchoscopy (Ion, Monarch) for peripheral lung nodules
• Therapeutic Bronchoscopy — Endobronchial valve placement for emphysema; bronchial thermoplasty for asthma; airway stenting; foreign body removal; hemoptysis management; cryotherapy; APC
• CT-Guided Lung Biopsy — Coordination with interventional radiology for peripheral lung lesions not accessible by bronchoscopy

Lung Cancer Diagnosis & Staging

• Lung Nodule Management — Fleischner Society guidelines; Lung-RADS; CT surveillance; PET-CT; bronchoscopic biopsy; CT-guided biopsy; VATS resection coordination
• Molecular Profiling — Comprehensive NGS panel (EGFR, ALK, ROS1, KRAS, MET, BRAF, RET, NTRK, HER2, PD-L1); liquid biopsy (ctDNA); coordination with oncology for treatment
• Mediastinal Staging — EBUS-TBNA; EUS-FNA; mediastinoscopy coordination

Why International Patients Choose Huadong Hospital Respiratory Medicine

• Geriatric Respiratory Medicine — Unique integration with China's premier geriatric medicine department; frailty-adjusted respiratory care for older adults
• Dupilumab for COPD — Type 2 inflammation-guided biologic therapy for COPD with eosinophilia
• Tezepelumab for Severe Asthma — Anti-TSLP biologic for severe uncontrolled asthma regardless of phenotype
• Sotatercept for PAH — Novel activin receptor ligand trap for pulmonary arterial hypertension
• Endobronchial Valve (Zephyr) — Bronchoscopic lung volume reduction for severe emphysema
• Navigational Bronchoscopy — Ion and Monarch robotic bronchoscopy for peripheral lung nodule biopsy
• Cost-Effectiveness — World-class respiratory care at significantly lower cost than equivalent treatment in Western countries

The CMCS Patient Journey

1. Initial Inquiry — Share your respiratory diagnosis, pulmonary function tests, CT chest imaging, sleep study results, and current medications with CMCS.
2. Medical Record Preparation — We translate and organize your records for specialist pre-consultation review.
3. Specialist Matching — We identify the most appropriate respiratory physician based on your condition — COPD, asthma, ILD, sleep apnea, respiratory infection, or lung cancer diagnosis.
4. Priority Scheduling — We secure a consultation with minimal waiting time.
5. Travel & Logistics — Assistance with visa invitation letters, accessible accommodation near Huadong Hospital, and Shanghai airport transfers.
6. Diagnostic Assessment — Full coordination of pulmonary function testing, CT chest, bronchoscopy, sleep study, and other required investigations.
7. Treatment Coordination — Full coordination of biologic therapy initiation, bronchoscopic procedures, NIV setup, and CPAP prescription.
8. Post-Consultation Follow-Up — Test result translation, treatment plan interpretation, inhaler technique guidance, and remote follow-up coordination after you return home.

Book a Consultation

If you have COPD, severe asthma, interstitial lung disease, sleep apnea, a respiratory infection, pulmonary hypertension, or a complex respiratory condition — CMCS can arrange a specialist consultation with Huadong Hospital's respiratory medicine team in Shanghai.

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