Professor Hao Junwei: Neuroimmunology and Complex Neurological Disease Specialist
Professor Hao Junwei is a senior neurologist, professor, doctoral supervisor, vice president of Xuanwu Hospital, and director of its Department of Neurology. His clinical and academic work focuses on neuroimmunological disease, autoimmune encephalitis, neuromyelitis optica spectrum disorder, inflammatory disorders of the central nervous system, and acute and chronic cerebrovascular disease.
International patients can learn more about the hospital, neurological services, and consultation preparation in our Xuanwu Hospital international patient guide.
Clinical and Academic Focus
- autoimmune encephalitis;
- neuromyelitis optica spectrum disorder;
- MOG antibody-associated disease;
- multiple sclerosis and related inflammatory disorders;
- immune-mediated myelitis and optic neuritis;
- complex or unexplained neurological inflammation;
- acute and chronic cerebrovascular disease;
- immunotherapy selection and monitoring; and
- second opinions after uncertain diagnosis or relapse.
Autoimmune Encephalitis
Autoimmune encephalitis occurs when the immune system attacks the brain. Symptoms can include memory loss, confusion, seizures, psychiatric change, abnormal movement, sleep disturbance, reduced consciousness, or autonomic instability.
Evaluation may include brain MRI, EEG, spinal-fluid testing, blood and spinal-fluid antibodies, infection studies, cancer screening, and metabolic or genetic testing. A negative antibody panel does not automatically exclude autoimmune disease, while a positive blood result must be interpreted with the clinical syndrome.
Treatment may include corticosteroids, intravenous immunoglobulin, plasma exchange, B-cell-directed therapy, other immunosuppressive medicines, seizure treatment, intensive care, and rehabilitation. Infection should be considered before strong immunosuppression.
Neuromyelitis Optica Spectrum Disorder
Neuromyelitis optica spectrum disorder can cause optic neuritis, transverse myelitis, persistent vomiting or hiccups, and brainstem or other neurological syndromes. Many patients have antibodies against aquaporin-4.
Acute attacks require prompt treatment to limit permanent disability. Long-term relapse prevention may involve biologic or conventional immunosuppressive therapy. Treatment differs from multiple sclerosis, making correct diagnosis essential.
MOG Antibody-Associated Disease
MOG antibody-associated disease can cause optic neuritis, myelitis, brain inflammation, or acute disseminated encephalomyelitis. Its course varies from a single episode to repeated relapses.
Antibody testing should use a validated cell-based method and be interpreted with timing, titer, and the clinical picture. Low-level positive results can be misleading when symptoms are not compatible.
Complex Neuroimmunology
Inflammatory neurological symptoms may resemble infection, cancer, metabolic disease, inherited disorders, toxic exposure, or vascular disease. Diagnosis often requires integrated review of imaging, spinal fluid, antibodies, pathology, treatment response, and the time course.
Professor Hao’s research includes large neuroimmunology cohorts and investigation of immune-cell and microglial mechanisms. Research findings may inform diagnosis and treatment development but do not replace individual assessment.
Immunotherapy and Safety
Long-term immune treatment should balance relapse prevention against infection, low blood counts, liver or kidney effects, and other complications. Screening and monitoring may include hepatitis, tuberculosis, immunoglobulin levels, vaccinations, blood tests, and reproductive planning.
Patients should not abruptly stop corticosteroids or immunosuppressive treatment without medical guidance.
Cerebrovascular Disease
Professor Hao also manages acute and chronic cerebrovascular disease. Sudden weakness, facial droop, speech difficulty, severe imbalance, vision loss, or an abrupt severe headache requires immediate local stroke evaluation. International travel must not delay emergency treatment.
Who May Consider a Consultation?
- patients with suspected or confirmed autoimmune encephalitis;
- patients with recurrent optic neuritis or transverse myelitis;
- patients with aquaporin-4 or MOG antibodies;
- patients whose diagnosis alternates between infection, inflammation, and another neurological disease;
- patients who relapse despite immunotherapy;
- patients experiencing serious treatment toxicity;
- patients with unexplained inflammatory MRI or spinal-fluid findings; or
- patients seeking a second opinion on long-term relapse prevention.
Medical Records to Prepare
- a concise neurological timeline, including relapses and recovery;
- brain, spinal-cord, and orbital MRI in original DICOM format;
- EEG recordings and reports;
- spinal-fluid cell count, protein, glucose, oligoclonal bands, infection, and antibody results;
- serum aquaporin-4, MOG, and autoimmune-encephalitis antibody reports with laboratory methods;
- cancer-screening and infectious-disease evaluations;
- all immune treatments with dates, doses, response, and side effects;
- current neurological function and rehabilitation assessments;
- a complete medication list; and
- a clear list of diagnostic and treatment questions.
Planning an International Consultation
Patients with new seizures, reduced consciousness, rapidly worsening weakness, severe breathing or swallowing problems, or stroke symptoms require immediate local emergency care.
Stable patients should confirm whether imaging and laboratory records can be reviewed. Remote medical-record review is subject to physician authorization, and final diagnosis or immunotherapy changes may require examination and repeat testing.
How CMCS Can Assist
CMCS – China Medical Concierge Shanghai is an independent medical concierge and health management company, not a hospital. We assist international patients with organizing and translating neurological records, identifying an appropriate specialist, requesting appointment availability, arranging interpretation, and planning medical travel in China.
Access to Professor Hao, remote review, testing, admission, or a specific immunotherapy is subject to doctor and hospital approval. CMCS does not guarantee appointments, treatment eligibility, or clinical outcomes.
- Email: contract@medicalsh.com
- WhatsApp: Contact us on WhatsApp
- Website: www.medicalsh.com
Important Note
Doctor titles, clinical roles, testing, treatment availability, and appointment arrangements may change. This profile is based on the supplied verified research document and is for general information only. It does not replace assessment by a qualified neurologist.
0 commenti