Professor Dong Jianzeng: Complex Arrhythmia and Persistent AF Specialist
Professor Dong Jianzeng is a senior cardiologist, professor, doctoral supervisor, deputy director of the Heart Center, and director of the Heart Failure and Cardiomyopathy Center at Beijing Anzhen Hospital. His clinical work focuses on atrial fibrillation, persistent and longstanding persistent AF, complex catheter ablation, other cardiac arrhythmias, pacemaker treatment, coronary disease, and the interaction between rhythm disorders and heart failure.
Clinical and Academic Focus
- persistent and longstanding persistent atrial fibrillation;
- paroxysmal atrial fibrillation;
- repeat ablation after recurrence;
- complex atrial tachycardia and flutter;
- pacemaker implantation;
- arrhythmia-related cardiomyopathy;
- atrial fibrillation with heart failure;
- risk-factor management after ablation; and
- second opinions before complex electrophysiology procedures.
Atrial Fibrillation
Atrial fibrillation is an irregular rhythm that can cause palpitations, fatigue, breathlessness, reduced exercise tolerance, heart failure, or no symptoms. It also increases the risk of stroke.
Management includes stroke prevention, heart-rate or rhythm control, and treatment of contributing conditions such as hypertension, obesity, sleep apnea, diabetes, thyroid disease, alcohol use, and valve disease.
Persistent Atrial Fibrillation
Persistent AF lasts longer than a brief self-terminating episode and often reflects more advanced electrical and structural remodeling of the atria. Catheter ablation can be more challenging than treatment for paroxysmal AF and recurrence is more common.
Selection should consider symptom burden, AF duration, atrial size, fibrosis, heart function, previous treatment, and patient goals.
The 2C3L Ablation Strategy
Professor Dong and colleagues developed a fixed “2C3L” strategy for persistent atrial fibrillation. The approach combines circumferential pulmonary-vein isolation with three linear ablation lines, generally involving the left-atrial roof, mitral isthmus, and cavotricuspid isthmus.
This strategy is not automatically suitable for every patient. Additional lesion sets can increase procedure complexity and may create atrial tachycardia if conduction block is incomplete. Mapping, anatomy, prior ablation, and operator judgment remain central.
Repeat Ablation
AF can recur because of pulmonary-vein reconnection, new triggers, atrial scarring, incomplete lines, or progression of underlying disease. A repeat procedure should review the first ablation report, electroanatomic maps, rhythm recordings, and risk-factor control.
AF and Heart Failure
Atrial fibrillation can worsen heart failure, while elevated filling pressure and atrial enlargement can promote AF. In selected patients, rhythm control and catheter ablation may improve symptoms and heart function.
Treatment may also include guideline-directed heart-failure medication, anticoagulation, device therapy, and management of coronary or valve disease.
Metabolic Therapy and AF Research
Professor Dong participated in research evaluating dapagliflozin and early recurrence after AF ablation. Medication choice should follow the patient’s approved indications, kidney function, diabetes and heart-failure status, and treating physician’s assessment.
Pacemaker Treatment
A pacemaker may be required for symptomatic slow rhythms, conduction block, or tachycardia-bradycardia syndrome. In some patients, rhythm or rate treatment can reveal significant bradycardia.
Device selection depends on heart function, atrial rhythm, expected pacing burden, and the need for conduction-system or resynchronization pacing.
Who May Consider a Consultation?
- patients with symptomatic persistent or longstanding persistent AF;
- patients with recurrent AF after one or more ablations;
- patients with complex atrial tachycardia or flutter;
- patients with AF and reduced heart function;
- patients comparing medication and ablation;
- patients needing review of a 2C3L or other substrate-based strategy;
- patients with tachycardia-bradycardia syndrome; or
- patients seeking a second opinion before repeat ablation.
Medical Records to Prepare
- a concise rhythm and treatment timeline;
- 12-lead ECGs captured during arrhythmia;
- Holter, patch, loop-recorder, or smartwatch recordings;
- echocardiography, transesophageal echo, and cardiac MRI;
- coronary and heart-failure evaluations;
- previous electrophysiology and ablation reports with maps;
- pacemaker records and recent device interrogation when relevant;
- kidney, liver, thyroid, electrolyte, glucose, and blood-count results;
- a complete medication list, especially anticoagulants and rhythm medicines; and
- a clear list of symptom and lifestyle goals.
Planning an International Consultation
Ongoing chest pain, fainting, severe breathlessness, sustained rapid rhythm, or stroke symptoms requires immediate local emergency care.
Stable patients should confirm whether rhythm recordings, imaging, and previous ablation data can be reviewed. Remote medical-record review requires physician authorization. Final procedure eligibility usually requires in-person cardiac and electrophysiology assessment.
How CMCS Can Assist
CMCS – China Medical Concierge Shanghai is an independent medical concierge and health management company, not a hospital. We assist international patients with organizing and translating cardiology records, identifying an appropriate specialist, requesting appointment availability, arranging interpretation, and planning medical travel in China.
Access to Professor Dong, remote review, ablation, pacemaker treatment, or a particular medicine is subject to doctor and hospital approval. CMCS does not guarantee appointments, procedure eligibility, device availability, or clinical outcomes.
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Important Note
Doctor titles, clinical roles, medicines, devices, procedures, and appointment arrangements may change. This profile is based on the supplied verified research document and is for general information only. It does not replace assessment by a qualified cardiac electrophysiology team.
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