Head & Neck Oncology at Fudan University Eye & ENT Hospital Shanghai | CMCS

Head & Neck Oncology at Fudan University Eye & ENT Hospital Shanghai | CMCS

Expert Head & Neck Cancer Care at China's Premier ENT Specialty Hospital

The Department of Head and Neck Oncology at Fudan University Eye & ENT Hospital (EENT Hospital) is one of China's most distinguished head and neck cancer centers, with a national reputation for excellence in the surgical and multidisciplinary management of thyroid cancer, laryngeal cancer, hypopharyngeal cancer, oral cavity cancer, oropharyngeal cancer, nasopharyngeal cancer, salivary gland tumors, and other head and neck malignancies. As China's only dedicated eye and ENT specialty hospital at the tertiary level, EENT Hospital's head and neck oncology department combines outstanding surgical expertise with a world-class research program and a fully integrated multidisciplinary approach, offering international patients access to some of China's most eminent head and neck surgeons and oncologists.

For international patients with thyroid cancer, laryngeal cancer, oral cancer, oropharyngeal cancer, nasopharyngeal cancer, or a salivary gland tumor — EENT Hospital's head and neck oncology department offers an unparalleled combination of surgical expertise, oncological capability, and research leadership. China Medical Concierge Shanghai (CMCS) provides seamless end-to-end coordination for international patients throughout their care journey at EENT Hospital.

About the Department

EENT Hospital's head and neck oncology department is a national key clinical specialty operating dedicated head and neck oncology surgical wards, a comprehensive head and neck oncology clinic, a thyroid cancer center, a multidisciplinary head and neck tumor board, a robotic head and neck surgery program, a reconstructive surgery service, and works in close collaboration with medical oncology, radiation oncology, pathology, radiology, and speech therapy through a fully integrated multidisciplinary team.

Faculty members publish regularly in leading head and neck oncology journals including Journal of Clinical Oncology, Head & Neck, Oral Oncology, Thyroid, and Annals of Surgical Oncology.

Cancer-Specific Expertise

Thyroid Cancer

EENT Hospital's thyroid cancer program is one of China's most comprehensive and highest-volume:

  • Papillary Thyroid Carcinoma (PTC) — Active surveillance for low-risk microPTC; hemithyroidectomy for low-risk PTC; total thyroidectomy for high-risk and bilateral disease; central neck dissection; lateral neck dissection for node-positive disease; radioactive iodine (RAI) ablation; TSH suppression therapy
  • Follicular Thyroid Carcinoma (FTC) — Total thyroidectomy; RAI for distant metastases; TSH suppression
  • Medullary Thyroid Carcinoma (MTC) — Total thyroidectomy with central neck dissection; RET mutation testing (germline and somatic); vandetanib and cabozantinib for advanced MTC; selpercatinib for RET-mutated MTC; pralsetinib; calcitonin and CEA monitoring; MEN2 family screening
  • Anaplastic Thyroid Carcinoma (ATC) — BRAF V600E testing; dabrafenib + trametinib for BRAF V600E ATC; pembrolizumab; spartalizumab; multimodal treatment with surgery, radiation, and systemic therapy
  • Differentiated Thyroid Cancer with Distant Metastases — RAI for RAI-avid metastases; lenvatinib and sorafenib for RAI-refractory DTC; cabozantinib second-line; selective RET inhibitors for RET-fusion DTC
  • Minimally Invasive Thyroid Surgery — Endoscopic thyroidectomy via bilateral axillo-breast approach (BABA); transoral endoscopic thyroidectomy vestibular approach (TOETVA); robotic thyroidectomy via axillary approach; scarless neck surgery for selected patients
  • Intraoperative Neuromonitoring (IONM) — Continuous IONM for recurrent laryngeal nerve preservation; intermittent IONM; nerve identification and preservation

Laryngeal Cancer

  • Early Glottic Cancer (T1-T2) — Transoral laser microsurgery (TLM) for voice preservation; CO2 laser cordectomy (type I-VI); radiation therapy as alternative for voice preservation; excellent oncological and functional outcomes
  • Supraglottic Cancer — Transoral laser supraglottic laryngectomy; open supraglottic laryngectomy; concurrent chemoradiation for organ preservation; total laryngectomy for advanced disease
  • Advanced Laryngeal Cancer (T3-T4) — Organ preservation with concurrent chemoradiation (cisplatin + radiation); total laryngectomy with tracheoesophageal voice prosthesis (TEP); neck dissection; free flap reconstruction
  • Voice Rehabilitation After Laryngectomy — Tracheoesophageal puncture (TEP) and voice prosthesis (Provox, Blom-Singer); electrolarynx; esophageal speech; speech therapy coordination

Hypopharyngeal Cancer

  • Early Hypopharyngeal Cancer — Transoral laser microsurgery; partial pharyngectomy; concurrent chemoradiation
  • Advanced Hypopharyngeal Cancer — Total laryngopharyngectomy with free flap reconstruction (radial forearm, anterolateral thigh, jejunum); concurrent chemoradiation for organ preservation; pembrolizumab + chemotherapy for recurrent/metastatic disease

Oral Cavity Cancer

  • Early Oral Cancer (T1-T2) — Transoral resection; sentinel lymph node biopsy (SLNB); elective neck dissection for high-risk T2; primary closure or local flap reconstruction
  • Advanced Oral Cancer (T3-T4) — Wide local excision with mandibulectomy or maxillectomy; free flap reconstruction (fibula, radial forearm, anterolateral thigh); neck dissection; adjuvant radiation ± chemotherapy
  • Robotic Oral Cavity Surgery — Transoral robotic surgery (TORS) for selected oral cavity and oropharyngeal tumors

Oropharyngeal Cancer

  • HPV-Positive Oropharyngeal Cancer — De-escalation strategies for favorable-risk HPV+ disease; transoral robotic surgery (TORS) with neck dissection; reduced-dose adjuvant radiation; concurrent chemoradiation
  • HPV-Negative Oropharyngeal Cancer — Standard concurrent chemoradiation; TORS for selected resectable tumors; pembrolizumab + chemotherapy for recurrent/metastatic disease

Nasopharyngeal Cancer (NPC)

  • Locoregionally Advanced NPC — Concurrent chemoradiation (cisplatin + IMRT); induction chemotherapy (gemcitabine + cisplatin) for high-risk disease; adjuvant capecitabine; EBV DNA monitoring
  • Recurrent NPC — Endoscopic nasopharyngectomy for selected local recurrences; re-irradiation (IMRT, proton); pembrolizumab and camrelizumab for recurrent/metastatic NPC; gemcitabine + cisplatin + camrelizumab
  • EBV-Targeted Therapy — EBV DNA as biomarker for treatment response and surveillance; EBV-specific T-cell therapy (investigational)

Salivary Gland Tumors

  • Parotid Tumors — Superficial and total parotidectomy with facial nerve preservation; facial nerve monitoring; pleomorphic adenoma; Warthin tumor; mucoepidermoid carcinoma; adenoid cystic carcinoma
  • Submandibular & Minor Salivary Gland Tumors — Surgical excision; neck dissection for malignant tumors
  • Adenoid Cystic Carcinoma (ACC) — Wide surgical resection; adjuvant radiation; lenvatinib; axatilimab for CSF1R-expressing ACC; repotrectinib for NTRK-fused ACC
  • Mucoepidermoid Carcinoma — Surgical resection; MAML2 fusion testing; adjuvant therapy for high-grade disease

Skin Cancer of the Head & Neck

  • Cutaneous Squamous Cell Carcinoma (cSCC) — Wide local excision; Mohs micrographic surgery coordination; sentinel lymph node biopsy; cemiplimab for advanced/metastatic cSCC; pembrolizumab
  • Melanoma of the Head & Neck — Wide local excision; sentinel lymph node biopsy; BRAF/MEK inhibitors for BRAF V600E melanoma; nivolumab + ipilimumab; pembrolizumab
  • Merkel Cell Carcinoma — Wide local excision; sentinel lymph node biopsy; avelumab; pembrolizumab

Reconstructive Surgery

EENT Hospital's reconstructive surgery program provides comprehensive free flap and pedicled flap reconstruction for head and neck defects after oncological resection:

  • Fibula Free Flap — Mandibular and maxillary reconstruction; osseointegrated dental implants for dental rehabilitation
  • Anterolateral Thigh (ALT) Free Flap — Soft tissue reconstruction for oral cavity, pharynx, and scalp defects
  • Radial Forearm Free Flap — Thin pliable flap for tongue, floor of mouth, and pharyngeal reconstruction
  • Jejunal Free Flap — Circumferential pharyngeal and esophageal reconstruction after total laryngopharyngectomy
  • Pectoralis Major Pedicled Flap — Salvage reconstruction; wound coverage

Why International Patients Choose EENT Hospital Head & Neck Oncology

  • Thyroid Cancer Expertise — High-volume thyroid cancer program; scarless endoscopic and robotic thyroidectomy; RET inhibitors for MTC; dabrafenib + trametinib for ATC
  • Transoral Laser Microsurgery — Voice-preserving CO2 laser surgery for early laryngeal cancer
  • Transoral Robotic Surgery (TORS) — Minimally invasive approach for oropharyngeal and selected oral cavity tumors
  • NPC Expertise — Endoscopic nasopharyngectomy for recurrent NPC; EBV-guided treatment
  • Comprehensive Reconstruction — Full range of free flap reconstruction for complex head and neck defects
  • Cost-Effectiveness — World-class head and neck cancer care at significantly lower cost than equivalent treatment in Western countries

The CMCS Patient Journey

  1. Initial Inquiry — Share your cancer diagnosis, pathology reports, imaging (CT, MRI, PET-CT), molecular profiling, and prior treatment history with CMCS.
  2. Medical Record Preparation — We translate and organize your records for specialist pre-consultation review.
  3. Specialist Matching — We identify the most appropriate head and neck surgeon or oncologist based on your tumor type and stage.
  4. MDT Submission — We facilitate pre-arrival case review by EENT Hospital's head and neck tumor board.
  5. Priority Scheduling — We secure a consultation with minimal waiting time.
  6. Travel & Logistics — Assistance with visa invitation letters, accommodation near EENT Hospital, and Shanghai airport transfers.
  7. Surgical Coordination — Full coordination of pre-operative assessment, surgical admission, and reconstructive surgery.
  8. Post-Operative Follow-Up — Pathology report translation, adjuvant therapy coordination, and remote follow-up after you return home.

Book a Consultation

If you have thyroid cancer, laryngeal cancer, oral cancer, oropharyngeal cancer, nasopharyngeal cancer, a salivary gland tumor, or another head and neck malignancy — CMCS can arrange a specialist consultation with EENT Hospital's head and neck oncology team in Shanghai.

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