Neonatology at Xinhua Hospital Shanghai | CMCS

One of China's Premier Centers for Newborn & Premature Infant Care

The Department of Neonatology at Xinhua Hospital — affiliated with Shanghai Jiao Tong University School of Medicine — is one of China's most distinguished and nationally recognized neonatology centers, with a national reputation for excellence in the care of extremely premature infants, critically ill newborns, neonatal surgery support, neonatal neurology, neonatal cardiology, and the management of complex neonatal conditions. As a hospital with world-class pediatric surgery, pediatric cardiology, and obstetrics under one roof, Xinhua Hospital's neonatology department offers uniquely comprehensive and integrated care for the most complex newborn cases. China Medical Concierge Shanghai (CMCS) provides seamless end-to-end coordination for international families throughout their newborn's care journey at Xinhua Hospital.

About the Department

The neonatology department is a national key clinical specialty operating a level III neonatal intensive care unit (NICU) with multiple subspecialty pods, a transport team for critically ill newborns, a neonatal neurology program with amplitude-integrated EEG (aEEG) and MRI capability, a neonatal cardiology program, a neonatal surgery support program, a neonatal nutrition program, a follow-up clinic for high-risk newborns, and works in close collaboration with pediatric surgery, pediatric cardiology, maternal-fetal medicine, and obstetrics through a fully integrated multidisciplinary neonatal team.

Faculty members publish regularly in leading neonatology journals including Pediatrics, Journal of Pediatrics, Neonatology, Archives of Disease in Childhood — Fetal and Neonatal Edition, and Early Human Development.

Extremely Premature Infant Care

Xinhua Hospital's extremely premature infant program is one of China's most experienced:

• Extreme Prematurity (22-28 weeks) — Periviability counseling; antenatal corticosteroids; magnesium sulfate for neuroprotection; delayed cord clamping; delivery room stabilization; one of China's most experienced extreme prematurity programs; survival rates benchmarked against international standards
• Respiratory Support — Non-invasive respiratory support (CPAP, HFNC, nHFOV, nSIPPV); surfactant replacement therapy (poractant alfa, beractant); INSURE technique; LISA/MIST (less invasive surfactant administration); high-frequency oscillatory ventilation (HFOV); conventional mechanical ventilation; one of China's most experienced neonatal respiratory support programs
• Bronchopulmonary Dysplasia (BPD) — Prevention: caffeine; vitamin A; postnatal corticosteroids (dexamethasone, budesonide); systemic and inhaled corticosteroids; diuretics; pulmonary vasodilators for BPD-associated PH; one of China's most experienced BPD programs
• Retinopathy of Prematurity (ROP) — Screening protocol; laser photocoagulation; intravitreal anti-VEGF (bevacizumab, ranibizumab) for zone I and posterior zone II ROP; one of China's most experienced ROP treatment programs; coordination with ophthalmology
• Intraventricular Hemorrhage (IVH) & Post-Hemorrhagic Hydrocephalus — IVH grading; serial head ultrasound; aEEG monitoring; ventricular access device (VAD); ventriculoperitoneal shunt coordination with neurosurgery; one of China's most experienced IVH management programs
• Necrotizing Enterocolitis (NEC) — Bell staging; medical management; surgical consultation; peritoneal drainage; laparotomy; bowel resection; intestinal rehabilitation; coordination with pediatric surgery
• Patent Ductus Arteriosus (PDA) — Conservative management; indomethacin; ibuprofen; paracetamol; transcatheter closure; surgical ligation; coordination with pediatric cardiology

Neonatal Neurology

• Hypoxic-Ischemic Encephalopathy (HIE) — Therapeutic hypothermia (whole-body cooling) for moderate-severe HIE; 72-hour cooling protocol; aEEG monitoring; MRI at day 5-7; erythropoietin neuroprotection; melatonin; one of China's most experienced HIE cooling programs
• Neonatal Seizures — aEEG and conventional EEG; phenobarbital; levetiracetam; phenytoin; pyridoxine for pyridoxine-dependent epilepsy; genetic evaluation (SCN2A, KCNQ2, CDKL5); one of China's most experienced neonatal seizure programs
• Neonatal Stroke — Arterial ischemic stroke; cerebral sinovenous thrombosis; MRI diagnosis; anticoagulation for CSVT; neurodevelopmental follow-up
• Neonatal MRI — Brain MRI at term-equivalent age for preterm infants; injury pattern classification; neurodevelopmental outcome prediction; one of China's most experienced neonatal MRI programs
• Metabolic Encephalopathy — Inborn errors of metabolism; organic acidemias; urea cycle disorders; amino acid disorders; emergency management; dietary treatment; coordination with metabolic medicine

Neonatal Cardiology

• Congenital Heart Disease (CHD) in Newborns — Echocardiographic diagnosis; prostaglandin E1 for duct-dependent lesions; balloon atrial septostomy (Rashkind) for TGA; coordination with pediatric cardiac surgery; one of China's most experienced neonatal CHD programs
• Critical CHD — Hypoplastic left heart syndrome (HLHS); pulmonary atresia; critical aortic stenosis; coarctation; TGA; Norwood stage I coordination; one of China's most experienced critical CHD neonatal programs
• Persistent Pulmonary Hypertension of the Newborn (PPHN) — Inhaled nitric oxide (iNO); sildenafil; milrinone; ECMO for refractory PPHN; one of China's most experienced PPHN programs
• Neonatal Arrhythmias — SVT; complete heart block; long QT syndrome; adenosine; propranolol; pacemaker coordination

Neonatal Surgery Support

Xinhua Hospital's unique integration of neonatology with world-class pediatric surgery enables seamless care for surgical newborns:

• Pre- and Post-Operative Neonatal Care — Optimization before surgery; post-operative NICU management; pain management; nutrition support; one of China's most experienced neonatal surgical support programs
• Esophageal Atresia (EA/TEF) — Pre-operative stabilization; post-operative ventilation; anastomotic leak management; stricture dilation; coordination with pediatric surgery
• Congenital Diaphragmatic Hernia (CDH) — Pre-operative stabilization; iNO; HFOV; ECMO for severe PPHN; post-operative care; coordination with pediatric surgery
• Gastroschisis & Omphalocele — Delivery room management; temperature regulation; fluid management; staged closure support
• Short Bowel Syndrome — Parenteral nutrition; intestinal rehabilitation; teduglutide (GLP-2 analogue) for intestinal adaptation; coordination with pediatric surgery and nutrition

Neonatal Infection & Immunology

• Neonatal Sepsis — Early and late-onset sepsis; culture-directed antibiotics; antifungal prophylaxis (fluconazole) for VLBW infants; IVIG for refractory sepsis; one of China's most experienced neonatal sepsis programs
• Congenital Infections (TORCH) — CMV: valganciclovir; HSV: acyclovir; toxoplasmosis: pyrimethamine + sulfadiazine; syphilis: penicillin; Zika: surveillance
• Neonatal Immune Thrombocytopenia — NAIT: IVIG; platelet transfusion; maternal treatment in subsequent pregnancies

Neonatal Nutrition & Growth

• Parenteral Nutrition — Individualized PN for VLBW and ELBW infants; amino acid and lipid optimization; PN-associated cholestasis prevention; one of China's most experienced neonatal PN programs
• Enteral Nutrition — Early minimal enteral feeding; human milk (donor breast milk program); human milk fortification; preterm formula; feeding intolerance management
• Donor Breast Milk Program — Pasteurized donor human milk for VLBW infants; NEC prevention; one of China's most experienced donor milk programs
• Growth Monitoring — Fenton growth charts; head circumference; weight velocity; extrauterine growth restriction prevention

High-Risk Newborn Follow-Up

• Neurodevelopmental Follow-Up — Bayley Scales of Infant Development; developmental assessment at 18-24 months corrected age; early intervention referral; one of China's most comprehensive NICU follow-up programs
• Hearing Screening — Universal newborn hearing screening (UNHS); OAE and ABR; early intervention for hearing loss; coordination with ENT for cochlear implantation
• Vision Follow-Up — ROP surveillance; ophthalmology coordination; refractive error screening
• Respiratory Follow-Up — BPD management; home oxygen; pulmonary function testing; RSV prophylaxis (palivizumab; nirsevimab)

Why International Patients Choose Xinhua Hospital Neonatology

• Extreme Prematurity Expertise — One of China's most experienced extreme prematurity programs; survival rates benchmarked against international standards; periviability care from 22 weeks
• Therapeutic Hypothermia for HIE — One of China's most experienced HIE cooling programs; 72-hour whole-body cooling; aEEG monitoring; MRI outcome assessment
• Integrated Pediatric Surgery — World-class pediatric surgery on-site; seamless neonatal surgical support; EA/TEF, CDH, gastroschisis, NEC
• Critical CHD Program — One of China's most experienced neonatal critical CHD programs; HLHS; TGA; PPHN with ECMO
• Donor Breast Milk Program — One of China's most experienced donor human milk programs; NEC prevention for VLBW infants
• Nirsevimab for RSV — Long-acting monoclonal antibody for RSV prevention in preterm and high-risk infants
• Cost-Effectiveness — World-class neonatal care at significantly lower cost than equivalent treatment in Western countries

The CMCS Patient Journey

1. Initial Inquiry — Share your newborn's diagnosis, gestational age, birth weight, NICU records, imaging, and current clinical status with CMCS.
2. Medical Record Preparation — We translate and organize your newborn's records for specialist pre-consultation review.
3. Specialist Matching — We identify the most appropriate neonatologist based on your newborn's condition — extreme prematurity, HIE, neonatal neurology, neonatal cardiology, surgical support, or infection.
4. Priority Scheduling — We secure a consultation with minimal waiting time; emergency transfer coordination available.
5. Travel & Logistics — Assistance with visa invitation letters, family accommodation near Xinhua Hospital, and Shanghai airport transfers; neonatal transport coordination.
6. NICU Admission Coordination — Full coordination of NICU admission, subspecialty consultations, and surgical planning.
7. Family Support — Translation support during NICU rounds; family communication; discharge planning.
8. Post-Discharge Follow-Up — Discharge summary translation, neurodevelopmental follow-up coordination, and remote follow-up after you return home.

Book a Consultation

If your newborn is premature, has hypoxic-ischemic encephalopathy, a congenital heart defect, a surgical condition, a metabolic disorder, or any complex neonatal condition — CMCS can arrange a specialist consultation with Xinhua Hospital's neonatology team in Shanghai.

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