Professor Yu Xinguang: Complex Brain and Skull Base Surgery Specialist
Professor Yu Xinguang is a senior neurosurgeon, professor, and director of the Institute of Neurosurgery at the First Medical Center of the Chinese PLA General Hospital in Beijing. His clinical and research work spans cerebrovascular disease, skull-base and deep-brain tumors, craniovertebral-junction disorders, traumatic brain injury, advanced brain function, brain networks, and brain-computer interfaces.
International patients can learn more about the hospital and specialist services in our Chinese PLA General Hospital international patient guide.
Clinical and Academic Focus
- brain aneurysms and vascular malformations;
- skull-base and deep-brain tumors;
- glioma and glioblastoma;
- craniovertebral-junction abnormalities;
- complex traumatic brain injury;
- high-function and brain-network preservation;
- focused ultrasound for movement disorders;
- brain-computer interface research; and
- second opinions before high-risk neurosurgery.
Cerebrovascular Neurosurgery
Brain aneurysms, arteriovenous malformations, cavernous malformations, and other vascular lesions can cause bleeding, seizures, headache, or neurological deficits. Treatment may include observation, microsurgery, endovascular treatment, radiosurgery, or a combined strategy.
The plan depends on lesion anatomy, rupture history, blood-flow pattern, patient age, symptoms, and procedural risk. Complex cases benefit from joint review by open and endovascular neurosurgical teams.
Skull-Base and Deep-Brain Tumors
Tumors near the skull base or deep structures can involve cranial nerves, major blood vessels, the brainstem, and hormonal pathways. Surgical planning aims to balance tumor control with preservation of vision, hearing, swallowing, facial movement, strength, and cognition.
Evaluation may include high-resolution MRI, CT of the skull base, vascular imaging, endocrine testing, hearing and visual assessment, and review by radiation oncology or other specialties.
Glioma and Glioblastoma
Gliomas arise from cells in the brain and vary from slow-growing tumors to aggressive glioblastoma. Diagnosis and treatment depend on tissue pathology and molecular markers, not imaging alone.
Surgery generally aims for the safest maximal removal while preserving neurological function. Treatment may also involve radiation, chemotherapy, tumor-treating fields, supportive care, or a clinical trial.
Professor Yu’s research has explored how extracellular vesicles and inflammatory microglia influence glioblastoma progression.
Craniovertebral-Junction Disorders
Conditions at the junction of the skull and upper cervical spine can compress the brainstem or spinal cord and cause pain, weakness, numbness, imbalance, swallowing difficulty, or breathing problems.
Treatment depends on stability, alignment, bone anatomy, neural compression, and the underlying cause. Some patients need decompression, fusion, reduction, or a combined approach.
Focused Ultrasound
Magnetic-resonance-guided focused ultrasound uses concentrated sound energy to create a precise lesion without a surgical incision. It may be considered for selected patients with medication-refractory essential tremor.
Professor Yu’s team participated in an early mainland China program using this technology. Eligibility depends on diagnosis, skull characteristics, previous treatment, and current device and hospital availability.
Brain Function and Brain-Computer Interfaces
Advanced neurosurgery increasingly uses functional mapping, electrophysiology, imaging, and brain-network analysis to preserve important abilities. Brain-computer interfaces remain a developing field with many applications still limited to approved research.
Professor Yu has led work in remote holographic surgical collaboration and invasive brain-computer-interface research. These technologies should not be interpreted as routinely available treatment.
Who May Consider a Consultation?
- patients with a complex brain aneurysm or vascular malformation;
- patients with a skull-base or deep-brain tumor;
- patients with newly diagnosed or recurrent glioma;
- patients with a craniovertebral-junction abnormality;
- patients advised to undergo high-risk neurosurgery;
- patients seeking function-preserving surgical planning;
- selected patients with medication-refractory essential tremor; or
- patients seeking a second opinion after previous neurosurgery.
Medical Records to Prepare
- a concise symptom, diagnosis, and treatment timeline;
- brain and spine MRI in original DICOM format;
- CT, CTA, MRA, and catheter angiography when relevant;
- functional imaging and neurophysiology reports;
- pathology slides, paraffin blocks, and molecular reports for tumors;
- previous operative and radiation records;
- visual, hearing, swallowing, and neurological assessments;
- a complete medication list, including anticoagulants and antiseizure drugs;
- short videos of tremor or movement symptoms when relevant; and
- a clear list of treatment goals and questions.
Planning an International Consultation
Sudden severe headache, new weakness, seizure, confusion, loss of consciousness, or rapidly worsening brainstem symptoms requires immediate local emergency care.
Stable patients should confirm whether original imaging and pathology can be reviewed. Remote medical-record review requires physician authorization. Final diagnosis and treatment eligibility usually require in-person neurological and neurosurgical assessment.
How CMCS Can Assist
CMCS – China Medical Concierge Shanghai is an independent medical concierge and health management company, not a hospital. We assist international patients with organizing and translating neurosurgical records, identifying an appropriate specialist, requesting appointment availability, arranging interpretation, and planning medical travel in China.
Access to Professor Yu, remote review, surgery, focused ultrasound, or a research program is subject to doctor and hospital approval. CMCS does not guarantee appointments, procedure eligibility, trial enrollment, or clinical outcomes.
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Important Note
Doctor titles, clinical roles, technologies, procedures, and appointment arrangements may change. This profile is based on the supplied verified research document and is for general information only. It does not replace assessment by a qualified neurosurgical team.
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