One of China's Premier Centers for Comprehensive Pediatric Care
The Department of Pediatrics at Xinhua Hospital — affiliated with Shanghai Jiao Tong University School of Medicine — is one of China's most distinguished and nationally recognized pediatric centers, with a national reputation for excellence in pediatric hematology and oncology, pediatric neurology, pediatric cardiology, pediatric endocrinology, pediatric gastroenterology, pediatric nephrology, and the management of complex childhood diseases. As one of China's highest-volume and most comprehensive pediatric programs, the department combines outstanding clinical expertise with a world-class research program, offering international families access to some of China's most eminent pediatric specialists. China Medical Concierge Shanghai (CMCS) provides seamless end-to-end coordination for international patients throughout their child's medical care journey at Xinhua Hospital.
About the Department
The pediatrics department is a national key clinical specialty operating dedicated pediatric inpatient wards, a pediatric intensive care unit (PICU), a pediatric hematology and oncology unit with bone marrow transplantation capability, a pediatric neurology unit with EEG and EMG laboratory, a pediatric cardiology unit with echocardiography, a pediatric endocrinology clinic, a pediatric gastroenterology and nutrition clinic, a pediatric nephrology clinic, a pediatric immunology and allergy clinic, and works in close collaboration with pediatric surgery, neonatology, and all pediatric subspecialties through a fully integrated multidisciplinary team.
Pediatric Hematology & Oncology
Xinhua Hospital's pediatric hematology and oncology program is one of China's most comprehensive:
Pediatric Leukemia
- Acute Lymphoblastic Leukemia (ALL) — Risk-stratified treatment (standard, high, very high risk); CCCG-ALL protocol; BFM-based regimens; MRD-guided therapy; blinatumomab for MRD-positive ALL; inotuzumab ozogamicin for relapsed B-ALL; tisagenlecleucel (CAR-T) for relapsed/refractory B-ALL; nelarabine for T-ALL; allogeneic SCT for high-risk; one of China's most experienced pediatric ALL programs
- Acute Myeloid Leukemia (AML) — AML-BFM protocol; gemtuzumab ozogamicin for CD33-positive; FLT3 inhibitors for FLT3-mutated; venetoclax combinations; allogeneic SCT for high-risk; one of China's most experienced pediatric AML programs
- Chronic Myeloid Leukemia (CML) — Imatinib; dasatinib; nilotinib; asciminib; allogeneic SCT for blast crisis
- Juvenile Myelomonocytic Leukemia (JMML) — Allogeneic SCT as only curative treatment; azacitidine bridge; one of China's most experienced JMML programs
Pediatric Solid Tumors
- Wilms Tumor (Nephroblastoma) — SIOP and COG protocols; nephrectomy; actinomycin D + vincristine; doxorubicin for high-risk; bilateral Wilms tumor management; one of China's most experienced Wilms tumor programs
- Neuroblastoma — INRG risk stratification; COJEC induction; tandem ASCT for high-risk; dinutuximab (anti-GD2) + isotretinoin maintenance; DFMO (difluoromethylornithine) maintenance; ALK inhibitors (crizotinib, lorlatinib) for ALK-mutated; one of China's most experienced neuroblastoma programs
- Medulloblastoma — Risk stratification (standard vs. high risk); surgery + craniospinal irradiation + chemotherapy; molecular subgrouping (WNT, SHH, Group 3, Group 4); vismodegib for SHH-activated; ONC201 for H3K27M-mutant; one of China's most experienced medulloblastoma programs
- Ewing Sarcoma — VIDE/VAC induction; local control (surgery and/or radiation); high-dose chemotherapy + ASCT for high-risk; regorafenib for relapsed; one of China's most experienced Ewing sarcoma programs
- Osteosarcoma — MAP protocol (methotrexate + doxorubicin + cisplatin); limb-salvage surgery coordination with orthopedics; mifamurtide (MTP-PE) for non-metastatic; regorafenib + gemcitabine for relapsed
- Rhabdomyosarcoma — IRS/COG risk stratification; VAC chemotherapy; local control; vinorelbine + actinomycin D for low-risk; one of China's most experienced RMS programs
- Hepatoblastoma — PRETEXT staging; PLADO chemotherapy; surgical resection; liver transplantation for unresectable; one of China's most experienced hepatoblastoma programs
- Retinoblastoma — Intra-arterial chemotherapy (IAC); intravitreal chemotherapy; systemic chemotherapy; laser; cryotherapy; enucleation; coordination with ophthalmology
- Germ Cell Tumors — BEP chemotherapy; surgical resection; gonadal preservation; fertility counseling
Pediatric Lymphoma
- Hodgkin Lymphoma — ABVD; BV-AVD; PET-adapted therapy; involved-field radiation; brentuximab vedotin for relapsed; nivolumab; pembrolizumab
- Non-Hodgkin Lymphoma — B-NHL: rituximab + chemotherapy; T-NHL: BFM protocols; ALCL: brentuximab vedotin + CHP; crizotinib for ALK-positive ALCL
Bone Marrow Transplantation
- Allogeneic SCT for leukemia, MDS, aplastic anemia, hemoglobinopathies, immunodeficiencies; matched sibling and unrelated donor; haploidentical (Beijing protocol); cord blood; CAR-T cell therapy; one of China's most experienced pediatric BMT programs
Pediatric Neurology
- Epilepsy — Comprehensive epilepsy program; video-EEG monitoring; genetic testing (SCN1A, KCNQ2, CDKL5, ARX); ketogenic diet; VNS; epilepsy surgery evaluation; SEEG; one of China's most experienced pediatric epilepsy programs
- Dravet Syndrome — Valproate + clobazam; stiripentol; fenfluramine (Fintepla); cannabidiol (Epidiolex); SCN1A mutation; avoidance of sodium channel blockers
- Infantile Spasms (West Syndrome) — ACTH; vigabatrin; prednisolone; TSC-associated: everolimus; one of China's most experienced infantile spasms programs
- Neuromuscular Diseases — Spinal muscular atrophy (SMA): nusinersen (Spinraza); onasemnogene abeparvovec (Zolgensma) for SMA type 1; risdiplam (Evrysdi); one of China's most experienced SMA programs; Duchenne muscular dystrophy: ataluren for nonsense mutations; exon-skipping (eteplirsen, golodirsen, viltolarsen, casimersen); gene therapy trials
- Metabolic & Neurogenetic Diseases — Lysosomal storage disorders; mucopolysaccharidoses; enzyme replacement therapy; substrate reduction therapy; gene therapy; one of China's most experienced pediatric metabolic disease programs
- Cerebral Palsy — Botulinum toxin; intrathecal baclofen; selective dorsal rhizotomy; rehabilitation coordination
- Neurodevelopmental Disorders — Autism spectrum disorder; ADHD; intellectual disability; developmental assessment; early intervention
Pediatric Cardiology
- Congenital Heart Disease (CHD) — Echocardiographic diagnosis; cardiac catheterization; interventional closure (ASD, VSD, PDA); balloon valvuloplasty; coordination with pediatric cardiac surgery; one of China's most experienced pediatric CHD programs
- Pediatric Arrhythmias — SVT; WPW; long QT syndrome; Brugada; CPVT; catheter ablation; ICD; genetic testing
- Pediatric Heart Failure — Dilated cardiomyopathy; myocarditis; sacubitril/valsartan; SGLT2 inhibitors; mechanical circulatory support; heart transplantation evaluation
- Kawasaki Disease — IVIG + aspirin; infliximab for IVIG-resistant; coronary artery aneurysm surveillance; one of China's most experienced Kawasaki disease programs
Pediatric Endocrinology
- Type 1 Diabetes — Insulin pump (CSII); CGM; closed-loop artificial pancreas; teplizumab for at-risk individuals; one of China's most experienced pediatric T1DM programs
- Growth Disorders — Growth hormone deficiency: recombinant GH; lonapegsomatropin (once-weekly GH); somapacitan; Turner syndrome: GH + estrogen; SGA: GH; SHOX deficiency: GH; one of China's most experienced pediatric growth disorder programs
- Precocious Puberty — GnRH agonist (leuprolide, triptorelin); central vs. peripheral; coordination with gynecologic endocrinology
- Congenital Hypothyroidism — Newborn screening; levothyroxine; monitoring; neurodevelopmental follow-up
- Congenital Adrenal Hyperplasia (CAH) — Hydrocortisone; fludrocortisone; salt supplementation; abiraterone + prednisolone for classic CAH; one of China's most experienced CAH programs
Pediatric Gastroenterology & Nutrition
- Inflammatory Bowel Disease (IBD) — Pediatric Crohn's disease and ulcerative colitis; exclusive enteral nutrition (EEN) for Crohn's; infliximab; adalimumab; vedolizumab; ustekinumab; risankizumab; tofacitinib; one of China's most experienced pediatric IBD programs
- Liver Disease — Biliary atresia; Wilson's disease; autoimmune hepatitis; PFIC; Alagille syndrome; liver transplantation evaluation; coordination with hepatology
- Pediatric Nutrition — Malnutrition; failure to thrive; enteral and parenteral nutrition; short bowel syndrome; one of China's most experienced pediatric nutrition programs
Pediatric Nephrology
- Nephrotic Syndrome — Corticosteroids; calcineurin inhibitors; rituximab for steroid-dependent/resistant; sparsentan for FSGS; one of China's most experienced pediatric nephrotic syndrome programs
- Pediatric Hypertension — Secondary hypertension workup; antihypertensive therapy; renal artery stenosis
- Pediatric Dialysis & Transplantation — Peritoneal dialysis; hemodialysis; kidney transplantation evaluation; coordination with nephrology
Pediatric Immunology & Allergy
- Primary Immunodeficiencies (PID) — SCID; XLA; CVID; CGD; WAS; genetic diagnosis; HSCT for severe PID; gene therapy; IVIG replacement; one of China's most experienced PID programs
- Autoinflammatory Diseases — SJIA: tocilizumab; canakinumab; AOSD; FMF: colchicine; anakinra; rilonacept; CAPS: canakinumab
- Pediatric Allergy — Food allergy; oral immunotherapy (OIT) for peanut (Palforzia); asthma; allergic rhinitis; atopic dermatitis; dupilumab for pediatric AD and asthma
Why International Patients Choose Xinhua Hospital Pediatrics
- One of China's Top Pediatric Centers — Nationally recognized across all pediatric subspecialties; comprehensive multidisciplinary team
- SMA Gene Therapy — Onasemnogene abeparvovec (Zolgensma) for SMA type 1; nusinersen; risdiplam; one of China's most experienced SMA programs
- CAR-T for Pediatric ALL — Tisagenlecleucel for relapsed/refractory B-ALL; one of China's most experienced pediatric CAR-T programs
- Dinutuximab for Neuroblastoma — Anti-GD2 immunotherapy + DFMO maintenance for high-risk neuroblastoma
- Fenfluramine for Dravet Syndrome — Fintepla for SCN1A-mutated Dravet syndrome; significant seizure reduction
- Cost-Effectiveness — World-class pediatric care at significantly lower cost than equivalent treatment in Western countries
The CMCS Patient Journey
- Initial Inquiry — Share your child's diagnosis, medical records, genetic test results, imaging, and prior treatment history with CMCS.
- Medical Record Preparation — We translate and organize your child's records for specialist pre-consultation review.
- Specialist Matching — We identify the most appropriate pediatric specialist based on your child's condition — hematology/oncology, neurology, cardiology, endocrinology, gastroenterology, nephrology, or immunology.
- MDT Submission — For oncology cases, we facilitate pre-arrival case review by the multidisciplinary pediatric tumor board.
- Priority Scheduling — We secure a consultation with minimal waiting time.
- Travel & Logistics — Assistance with visa invitation letters, family-friendly accommodation near Xinhua Hospital, and Shanghai airport transfers.
- Treatment Coordination — Full coordination of chemotherapy, targeted therapy, BMT, or other treatment scheduling.
- Post-Treatment Follow-Up — Treatment report translation, result interpretation, and remote follow-up coordination after you return home.
Book a Consultation
If your child has leukemia, a solid tumor, epilepsy, a neuromuscular disease, congenital heart disease, a metabolic disorder, or any complex pediatric condition — CMCS can arrange a specialist consultation with Xinhua Hospital's pediatrics team in Shanghai.
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