Neurosurgery at Changhai Hospital Shanghai | CMCS

Expert Brain, Spine & Cerebrovascular Surgery at One of Shanghai's Premier Military Medical Centers

The Department of Neurosurgery at Changhai Hospital — affiliated with Naval Medical University (Second Military Medical University) — is one of Shanghai's most distinguished neurosurgery centers, with a national reputation for excellence in brain tumor surgery, cerebrovascular surgery, spinal cord surgery, functional neurosurgery, and the management of complex neurological conditions requiring surgical intervention. With a strong military medical heritage emphasizing neurotrauma and complex reconstruction, Changhai Hospital's neurosurgery department combines outstanding surgical expertise with a world-class research program, offering international patients access to some of China's most eminent neurosurgeons.

For international patients with a brain tumor, cerebrovascular disease, spinal cord condition, or a complex neurological condition requiring surgery — Changhai Hospital's neurosurgery department offers an unparalleled combination of surgical expertise, neuromonitoring capability, and research leadership. China Medical Concierge Shanghai (CMCS) provides seamless end-to-end coordination for international patients throughout their neurosurgical care journey at Changhai Hospital.

About the Department

Changhai Hospital's neurosurgery department is a national key clinical specialty operating dedicated neurosurgical wards, a neurosurgical intensive care unit (NICU), multiple neurosurgical operating theaters with intraoperative MRI (iMRI), neuronavigation, intraoperative neurophysiological monitoring (IONM), fluorescence-guided surgery (5-ALA), and awake craniotomy capability, a cerebrovascular surgery program, a neuroendoscopy program, a functional neurosurgery program, and works in close collaboration with neurology, neuroradiology, radiation oncology, and rehabilitation through a fully integrated multidisciplinary neuro-oncology tumor board.

Faculty members publish regularly in leading neurosurgery journals including Journal of Neurosurgery, Neurosurgery, Acta Neurochirurgica, World Neurosurgery, and Journal of Neuro-Oncology.

Brain Tumor Surgery

Glioma Surgery

• High-Grade Glioma (GBM, Grade 4) — Maximum safe resection with intraoperative MRI (iMRI) for real-time residual tumor assessment; 5-ALA fluorescence-guided surgery for tumor visualization; awake craniotomy with cortical and subcortical mapping for eloquent area tumors; intraoperative neurophysiological monitoring (IONM); temozolomide + radiation; tumor treating fields (TTFields/Optune); bevacizumab for recurrent GBM; MGMT methylation and IDH mutation testing
• Low-Grade Glioma (Grade 2-3) — Awake craniotomy for eloquent area tumors; maximum safe resection; neuronavigation; iMRI; IDH1/2 mutation; 1p/19q codeletion; TERT promoter; PCV chemotherapy for 1p/19q codeleted oligodendroglioma; temozolomide for IDH-mutant astrocytoma; vorasidenib for IDH-mutant grade 2-3 glioma
• Pediatric Brain Tumors — Medulloblastoma; ependymoma; pilocytic astrocytoma; DIPG; coordination with pediatric oncology

Meningioma Surgery

• Convexity & Parasagittal Meningioma — Simpson grade I-II resection; sinus reconstruction for parasagittal meningiomas; neuronavigation
• Skull Base Meningioma — Sphenoid wing; cavernous sinus; petroclival; foramen magnum; cranial nerve preservation; staged surgery for large tumors
• Stereotactic Radiosurgery (SRS) — Gamma Knife and CyberKnife for small-medium meningiomas; post-operative SRS for residual tumor; coordination with radiation oncology
• Recurrent Meningioma — Re-resection; SRS; systemic therapy (somatostatin analogues, bevacizumab, pembrolizumab for high-grade meningioma)

Pituitary Tumors

• Endoscopic Endonasal Transsphenoidal Surgery (EETS) — Endoscopic pituitary adenoma resection; extended approaches for suprasellar and parasellar extension; coordination with rhinology and endocrinology; one of Shanghai's most experienced EETS programs
• Functioning Adenomas — Acromegaly (GH-secreting); Cushing's disease (ACTH-secreting); prolactinoma (dopamine agonists first-line; surgery for resistant cases); TSH-secreting adenoma
• Non-Functioning Adenomas — Surgery for visual compromise or large tumors; post-operative radiation for residual tumor
• Craniopharyngioma — Endoscopic endonasal and transcranial approaches; radiation for residual tumor; BRAF V600E inhibitors for papillary craniopharyngioma

Other Brain Tumors

• Brain Metastases — Surgical resection for large or symptomatic metastases; stereotactic radiosurgery (SRS) for 1-4 metastases; whole brain radiation therapy (WBRT) with hippocampal avoidance; laser interstitial thermal therapy (LITT) for deep or recurrent metastases
• Primary CNS Lymphoma (PCNSL) — Stereotactic biopsy for diagnosis; high-dose methotrexate-based chemotherapy; autologous stem cell transplantation; whole brain radiation
• Ependymoma — Maximum safe resection; radiation; ZFTA fusion testing; coordination with oncology
• Hemangioblastoma — Surgical resection; VHL disease screening; preoperative embolization for large tumors

Cerebrovascular Surgery

Intracranial Aneurysms

• Microsurgical Clipping — For ruptured and unruptured aneurysms; pterional, orbitozygomatic, and far lateral approaches; intraoperative angiography; IONM; one of Shanghai's most experienced aneurysm clipping programs
• Endovascular Coiling & Flow Diversion — Coil embolization; flow diverter (Pipeline embolization device — PED); WEB device for wide-neck bifurcation aneurysms; coordination with neurointerventional radiology
• Subarachnoid Hemorrhage (SAH) Management — Nimodipine for vasospasm prevention; transcranial Doppler monitoring; endovascular vasospasm treatment; external ventricular drain (EVD); ventriculoperitoneal (VP) shunt for hydrocephalus

Arteriovenous Malformations (AVM)

• Microsurgical AVM Resection — For Spetzler-Martin grade I-III AVMs; preoperative embolization; intraoperative angiography; IONM
• Stereotactic Radiosurgery (SRS) — Gamma Knife for small-medium AVMs; obliteration rates >80% at 3 years
• Multimodal Treatment — Embolization + surgery or SRS for complex AVMs

Cavernous Malformations

• Microsurgical resection for symptomatic cavernomas; brainstem cavernoma surgery; IONM; laser interstitial thermal therapy (LITT) for deep cavernomas

Moyamoya Disease

• Revascularization Surgery — Direct bypass (STA-MCA anastomosis); indirect bypass (EDAS, EMS, EMAS); combined direct + indirect bypass; one of Shanghai's most experienced moyamoya surgery programs
• Pediatric Moyamoya — Early revascularization to prevent stroke; indirect bypass preferred for children

Carotid Artery Disease

• Carotid Endarterectomy (CEA) — For symptomatic and high-grade asymptomatic carotid stenosis; eversion and conventional CEA; patch angioplasty; IONM
• Carotid Artery Stenting (CAS) — Coordination with neurointerventional radiology

Functional Neurosurgery

• Deep Brain Stimulation (DBS) — Parkinson's disease (STN and GPi targets); essential tremor (VIM target); dystonia; OCD; awake DBS with microelectrode recording; asleep DBS with intraoperative MRI; one of Shanghai's most experienced DBS programs
• Epilepsy Surgery — Presurgical evaluation (video-EEG, MRI, PET, MEG, SEEG); temporal lobectomy; lesionectomy; corpus callosotomy; vagus nerve stimulation (VNS); responsive neurostimulation (RNS); SEEG-guided radiofrequency thermocoagulation; laser interstitial thermal therapy (LITT) for MRI-guided ablation
• Trigeminal Neuralgia — Microvascular decompression (MVD — gold standard); Gamma Knife radiosurgery; percutaneous procedures (balloon compression, glycerol rhizotomy, radiofrequency thermocoagulation)
• Hemifacial Spasm — Microvascular decompression (MVD); botulinum toxin injection
• Spasticity — Intrathecal baclofen pump; selective dorsal rhizotomy for pediatric spasticity

Neurotrauma

Changhai Hospital's military medical heritage gives it particular expertise in neurotrauma management:

• Traumatic Brain Injury (TBI) — Emergency craniotomy for epidural and subdural hematoma; decompressive craniectomy for refractory intracranial hypertension; ICP monitoring; cranioplasty with custom titanium or PEEK implants
• Penetrating Brain Injury — Debridement; foreign body removal; dural repair
• Spinal Cord Injury — Emergency decompression and stabilization; methylprednisolone; rehabilitation coordination

Why International Patients Choose Changhai Neurosurgery

• Intraoperative MRI (iMRI) — Real-time residual tumor assessment during glioma surgery; maximizes extent of resection
• Awake Craniotomy — Cortical and subcortical mapping for eloquent area tumors; language and motor preservation
• 5-ALA Fluorescence Surgery — Fluorescence-guided GBM resection for improved tumor visualization
• Moyamoya Expertise — One of Shanghai's most experienced moyamoya revascularization programs
• DBS Leadership — One of Shanghai's most experienced DBS programs for Parkinson's disease and movement disorders
• Military Neurotrauma Heritage — Extensive experience in complex TBI and penetrating brain injury management
• Cost-Effectiveness — World-class neurosurgical care at significantly lower cost than equivalent treatment in Western countries

The CMCS Patient Journey

1. Initial Inquiry — Share your neurological diagnosis, MRI/CT brain and spine imaging, pathology reports, and prior treatment history with CMCS.
2. Medical Record Preparation — We translate and organize your records for specialist pre-consultation review.
3. Specialist Matching — We identify the most appropriate neurosurgeon based on your condition — brain tumor, cerebrovascular disease, functional neurosurgery, or spinal cord surgery.
4. MDT Submission — We facilitate pre-arrival case review by Changhai's neuro-oncology or cerebrovascular MDT.
5. Priority Scheduling — We secure a consultation with minimal waiting time.
6. Travel & Logistics — Assistance with visa invitation letters, accommodation near Changhai Hospital, and Shanghai airport transfers.
7. Surgical Coordination — Full coordination of pre-operative assessment, surgical admission, and NICU care.
8. Post-Operative Follow-Up — Pathology report translation, adjuvant therapy coordination, and remote follow-up after you return home.

Book a Consultation

If you have a brain tumor, cerebrovascular disease, Parkinson's disease, epilepsy, trigeminal neuralgia, or a complex neurological condition requiring surgery — CMCS can arrange a specialist consultation with Changhai Hospital's neurosurgery team in Shanghai.

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