Advanced Radiation Therapy at China's Premier Cancer Center
The Department of Radiation Oncology at Fudan University Shanghai Cancer Center (FUSCC) is one of China's most distinguished and technologically advanced radiation oncology programs, offering the full spectrum of modern radiation therapy techniques — from intensity-modulated radiation therapy (IMRT) and stereotactic body radiotherapy (SBRT) to proton beam therapy — for patients with all types of cancer. As an integral component of FUSCC's multidisciplinary cancer care model, the radiation oncology department works in close collaboration with surgical and medical oncology teams to deliver personalized, evidence-based radiation therapy as part of comprehensive cancer treatment plans.
FUSCC's radiation oncology department is one of the few centers in Shanghai with access to proton beam therapy — the most advanced form of radiation therapy available — offering patients with selected cancers the potential for superior tumor control with significantly reduced radiation dose to surrounding normal tissues compared to conventional photon-based radiation. China Medical Concierge Shanghai (CMCS) provides seamless end-to-end coordination for international patients seeking radiation therapy at FUSCC.
About the Department
FUSCC's radiation oncology department is a national key clinical specialty operating multiple state-of-the-art linear accelerators (LINACs) with advanced imaging and treatment delivery capabilities, a proton therapy center, a brachytherapy suite, a dedicated treatment planning team, and subspecialty radiation oncology clinics for breast cancer, lung cancer, head and neck cancer, gastrointestinal cancers, gynecologic cancers, and central nervous system tumors.
The department's treatment planning team uses the most advanced treatment planning systems and image-guided radiation therapy (IGRT) technologies to ensure precise, reproducible radiation delivery with daily verification of patient positioning and tumor location. Faculty members publish regularly in leading radiation oncology journals including International Journal of Radiation Oncology, Biology, Physics (Red Journal), Radiotherapy and Oncology, Journal of Clinical Oncology, and Lancet Oncology.
Radiation Therapy Technologies
Proton Beam Therapy
Proton beam therapy is the most advanced form of radiation therapy available, offering a fundamental physical advantage over conventional X-ray (photon) radiation: protons deposit the majority of their energy at a precise depth within the body (the Bragg peak) and then stop, delivering minimal exit dose to tissues beyond the tumor. This physical property enables:
- Superior Normal Tissue Sparing — Significantly reduced radiation dose to critical structures adjacent to the tumor, including the heart, lungs, spinal cord, brainstem, optic nerves, and bowel
- Reduced Long-Term Side Effects — Lower risk of radiation-induced secondary cancers, cardiac toxicity, pulmonary fibrosis, and other late effects — particularly important for pediatric patients and young adults
- Dose Escalation — Ability to safely deliver higher radiation doses to the tumor while maintaining acceptable normal tissue doses, potentially improving local control
Indications for Proton Therapy at FUSCC:
- Pediatric Cancers — Brain tumors (medulloblastoma, ependymoma, craniopharyngioma), rhabdomyosarcoma, Ewing sarcoma, and other pediatric malignancies; proton therapy is the preferred radiation modality for children due to dramatically reduced integral dose and long-term toxicity
- Head & Neck Cancer — Nasopharyngeal cancer, oropharyngeal cancer, sinonasal tumors, and skull base tumors; reduced xerostomia, dysphagia, and hearing loss compared to photon IMRT
- Brain & CNS Tumors — Glioma, meningioma, craniopharyngioma, and pituitary tumors; reduced neurocognitive toxicity
- Thoracic Cancers — Lung cancer, esophageal cancer, and mediastinal tumors; reduced cardiac and pulmonary dose
- Breast Cancer — Left-sided breast cancer requiring post-mastectomy or regional nodal radiation; dramatically reduced cardiac dose compared to photon techniques
- Gastrointestinal Cancers — Hepatocellular carcinoma, cholangiocarcinoma, and pancreatic cancer; reduced bowel and liver dose
- Prostate Cancer — Hypofractionated proton therapy for localized prostate cancer; reduced rectal and bladder dose
- Chordoma & Chondrosarcoma — Skull base and spinal chordoma; proton/carbon ion therapy for superior local control of these radioresistant tumors
- Re-irradiation — For selected patients requiring radiation to previously irradiated fields; proton therapy minimizes cumulative dose to critical structures
Intensity-Modulated Radiation Therapy (IMRT) & VMAT
IMRT and volumetric modulated arc therapy (VMAT) are the standard of care for most cancer sites at FUSCC, delivering highly conformal radiation dose distributions that closely conform to the tumor shape while minimizing dose to adjacent normal tissues:
- Simultaneous integrated boost (SIB) for dose escalation to high-risk volumes
- Adaptive radiation therapy (ART) with replanning during treatment for anatomical changes
- MR-guided radiation therapy for superior soft tissue visualization
Stereotactic Body Radiotherapy (SBRT) / SABR
SBRT delivers ablative radiation doses in 1-5 fractions with extreme precision, achieving local control rates comparable to surgery for selected indications:
- Early-Stage Lung Cancer — SBRT as definitive treatment for medically inoperable stage I NSCLC; local control rates >90%
- Liver Tumors — SBRT for HCC and liver metastases; alternative to RFA for lesions not amenable to ablation
- Spinal Metastases — Spine SBRT for pain control and local tumor control; separation surgery + SBRT for epidural disease
- Oligometastatic Disease — SBRT for 1-5 metastatic lesions in lung, liver, adrenal, and lymph nodes; curative-intent local ablative therapy
- Prostate Cancer — Ultra-hypofractionated SBRT (5 fractions) for localized prostate cancer
- Pancreatic Cancer — SBRT as consolidation after chemotherapy for locally advanced PDAC
Stereotactic Radiosurgery (SRS)
- Brain Metastases — Single-fraction or fractionated SRS for 1-10 brain metastases; whole brain radiation therapy avoidance
- Meningioma — SRS for small or residual meningiomas
- Acoustic Neuroma — SRS as alternative to surgery for small to medium vestibular schwannomas
- AVM — SRS for cerebral arteriovenous malformations
- Trigeminal Neuralgia — SRS as non-invasive treatment option
Brachytherapy
- Cervical Cancer — Image-guided adaptive brachytherapy (IGABT) with MRI-based planning; high-dose-rate (HDR) intracavitary and interstitial brachytherapy
- Endometrial Cancer — Vaginal vault brachytherapy after hysterectomy
- Prostate Cancer — LDR seed implantation and HDR brachytherapy
- Breast Cancer — Accelerated partial breast irradiation (APBI) with interstitial brachytherapy
Disease-Site Radiation Oncology Expertise
Breast Cancer Radiation
- Post-lumpectomy whole breast irradiation with hypofractionation (15-16 fractions)
- Ultra-hypofractionation (5 fractions) for selected patients
- Post-mastectomy radiation therapy (PMRT) with regional nodal irradiation
- Proton therapy for left-sided breast cancer to minimize cardiac dose
- Deep inspiration breath hold (DIBH) for cardiac sparing
Head & Neck Cancer Radiation
- IMRT for nasopharyngeal, oropharyngeal, laryngeal, and oral cavity cancers
- Concurrent chemoradiation with cisplatin
- Proton therapy for selected cases to reduce xerostomia and dysphagia
- Re-irradiation for recurrent head and neck cancer
Lung Cancer Radiation
- SBRT for early-stage medically inoperable NSCLC
- Concurrent chemoradiation for locally advanced NSCLC; durvalumab consolidation
- Prophylactic cranial irradiation for SCLC
- Palliative radiation for symptomatic metastases
Gastrointestinal Cancer Radiation
- Neoadjuvant chemoradiation for rectal cancer (long-course) and short-course radiation
- Concurrent chemoradiation for esophageal and anal cancer
- SBRT for liver tumors and pancreatic cancer
- IORT (intraoperative radiation therapy) for locally recurrent rectal cancer
Why International Patients Choose FUSCC Radiation Oncology
- Proton Therapy Access — One of Shanghai's few centers offering proton beam therapy for selected cancers requiring superior normal tissue sparing
- Technological Leadership — State-of-the-art LINACs, MR-guided radiation, adaptive radiotherapy, and advanced treatment planning
- SBRT Expertise — Ablative SBRT for early lung cancer, liver tumors, spinal metastases, and oligometastatic disease
- Multidisciplinary Integration — Radiation oncology fully integrated into FUSCC's tumor board-driven multidisciplinary care model
- Brachytherapy Excellence — Image-guided adaptive brachytherapy for cervical cancer and other gynecologic malignancies
- Cost-Effectiveness — World-class radiation therapy including proton therapy at significantly lower cost than equivalent treatment in Western countries
The CMCS Patient Journey
- Initial Inquiry — Share your cancer diagnosis, imaging (CT, MRI, PET-CT), pathology reports, prior treatment history, and radiation therapy indication with CMCS.
- Medical Record Preparation — We translate and organize your records for specialist pre-consultation review.
- Specialist Matching — We identify the most appropriate radiation oncologist based on your tumor type and radiation therapy indication.
- MDT Submission — Where appropriate, we facilitate pre-arrival case review by FUSCC's multidisciplinary tumor board.
- Priority Scheduling — We secure a radiation oncology consultation and treatment planning appointment with minimal waiting time.
- Travel & Logistics — Assistance with visa invitation letters, accommodation near FUSCC for the duration of radiation treatment, and Shanghai airport transfers.
- Treatment Coordination — Full coordination of simulation CT, treatment planning, daily treatment sessions, and on-treatment review appointments.
- Post-Treatment Follow-Up — Treatment summary translation, response assessment coordination, and remote follow-up after you return home.
Book a Consultation
If you are seeking expert radiation therapy in Shanghai — whether for proton therapy, SBRT, IMRT, brachytherapy, or a second opinion on a radiation therapy plan — CMCS can arrange a specialist consultation with FUSCC's radiation oncology team.
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