Pediatric Pulmonology at Fudan University Children's Hospital Shanghai | CMCS

Expert Lung & Respiratory Disease Care for Children at China's Premier Children's Hospital

The Department of Pulmonology at Fudan University Children's Hospital (FUCH) is one of China's most distinguished pediatric pulmonology centers, with a national reputation for excellence in the diagnosis and management of asthma, interstitial lung disease, rare lung diseases, cystic fibrosis, primary ciliary dyskinesia, bronchiectasis, and respiratory complications of systemic diseases in children. The department combines outstanding clinical expertise with a world-class research program and a fully integrated multidisciplinary approach, offering international families access to some of China's most eminent pediatric pulmonologists and the latest evidence-based treatments for complex childhood respiratory conditions.

For international families with a child with difficult-to-control asthma, a rare interstitial lung disease, cystic fibrosis, primary ciliary dyskinesia, or a complex respiratory diagnosis — FUCH's pulmonology department represents one of the most compelling destinations in Asia. China Medical Concierge Shanghai (CMCS) provides seamless end-to-end coordination for international families throughout their child's care journey at FUCH.

About the Department

FUCH's pulmonology department is a national key clinical specialty operating dedicated pediatric pulmonology inpatient wards, a comprehensive outpatient pulmonology clinic, a pulmonary function laboratory, a bronchoscopy suite, a sleep laboratory, a cystic fibrosis and bronchiectasis clinic, an interstitial lung disease clinic, and works in close collaboration with allergy and immunology, infectious disease, genetics, and thoracic surgery through a fully integrated multidisciplinary team.

Faculty members publish regularly in leading pediatric pulmonology journals including American Journal of Respiratory and Critical Care Medicine, Thorax, Pediatric Pulmonology, European Respiratory Journal, and Journal of Allergy and Clinical Immunology.

Conditions Treated

Asthma & Allergic Airway Disease

• Mild-Moderate Asthma — Inhaled corticosteroids (ICS); LABA combinations; leukotriene receptor antagonists; step-up and step-down therapy based on control assessment
• Severe & Difficult-to-Treat Asthma — Systematic evaluation for treatable traits; high-dose ICS/LABA; tiotropium; azithromycin for neutrophilic asthma
• Severe Eosinophilic Asthma — Biologic therapy: mepolizumab, benralizumab, dupilumab, tezepelumab; FeNO-guided therapy
• Allergic Asthma with Comorbid Allergic Rhinitis — Omalizumab for IgE-mediated allergic asthma; allergen immunotherapy
• Exercise-Induced Bronchoconstriction — Pre-exercise SABA; ICS optimization; montelukast
• Asthma in Preschool Children — Episodic viral wheeze vs. multi-trigger wheeze; ICS and LTRA; parent education

Interstitial Lung Disease (chILD)

• Surfactant Dysfunction Disorders — SFTPB, SFTPC, ABCA3, and NKX2-1 mutations; hydroxychloroquine; corticosteroids; lung transplantation for severe cases
• Neuroendocrine Cell Hyperplasia of Infancy (NEHI) — Supportive care; supplemental oxygen; natural history counseling
• Pulmonary Interstitial Glycogenosis (PIG) — Corticosteroids; supportive care
• Hypersensitivity Pneumonitis — Antigen avoidance; corticosteroids; mycophenolate mofetil
• Connective Tissue Disease-Associated ILD — Mycophenolate mofetil; nintedanib for progressive fibrosing ILD; tocilizumab for SSc-ILD
• Sarcoidosis — Corticosteroids; methotrexate; hydroxychloroquine
• Pulmonary Alveolar Proteinosis (PAP) — Whole lung lavage; GM-CSF inhalation; rituximab for autoimmune PAP
• Lymphangioleiomyomatosis (LAM) — Sirolimus; lung transplantation for advanced disease

Cystic Fibrosis (CF)

• CF Diagnosis & Monitoring — Sweat chloride testing; CFTR mutation analysis; pulmonary function monitoring; CT surveillance; sputum microbiology
• CFTR Modulator Therapy — Elexacaftor/tezacaftor/ivacaftor (Trikafta/Kaftrio) for F508del and other responsive mutations; ivacaftor (Kalydeco) for gating mutations; lumacaftor/ivacaftor for F508del homozygous
• Airway Clearance — High-frequency chest wall oscillation (HFCWO); oscillating PEP devices; hypertonic saline; dornase alfa
• CF Pulmonary Exacerbations — IV antibiotic therapy for Pseudomonas and other pathogens; inhaled tobramycin and aztreonam maintenance
• CF Complications — CF-related diabetes; CF liver disease; distal intestinal obstruction syndrome; allergic bronchopulmonary aspergillosis (ABPA)

Primary Ciliary Dyskinesia (PCD)

• PCD Diagnosis — Nasal nitric oxide; transmission electron microscopy; high-speed video microscopy; genetic panel testing (DNAI1, DNAI2, DNAH5, DNAH11, and others)
• PCD Management — Airway clearance; antibiotic therapy for exacerbations; management of situs inversus and heterotaxy; hearing loss management

Bronchiectasis

• Non-CF Bronchiectasis — Underlying cause identification (PCD, immunodeficiency, post-infectious, aspiration); airway clearance; antibiotic therapy; inhaled antibiotics for chronic Pseudomonas colonization
• Post-Infectious Bronchiectasis — Management of sequelae of severe pneumonia, pertussis, and measles

Rare & Structural Lung Diseases

• Congenital Pulmonary Airway Malformation (CPAM) — Surveillance and surgical resection coordination
• Pulmonary Sequestration — Surgical resection coordination
• Pulmonary Arteriovenous Malformation — Transcatheter embolization coordination
• Tracheobronchomalacia — Positive pressure ventilation; surgical aortopexy for severe cases
• Vascular Ring & Airway Compression — Surgical correction coordination with cardiac surgery
• Pulmonary Hypertension — Vasoreactivity testing; sildenafil, bosentan, and selexipag; IV epoprostenol for severe PAH

Sleep-Disordered Breathing

• Obstructive Sleep Apnea (OSA) — Polysomnography; adenotonsillectomy coordination with ENT; CPAP for residual OSA; weight management
• Central Sleep Apnea & Hypoventilation — Congenital central hypoventilation syndrome (CCHS/Ondine's curse); PHOX2B mutation testing; home ventilation
• Obesity Hypoventilation — NIV; weight management

Respiratory Infections & Complications

• Recurrent Pneumonia — Systematic evaluation for underlying immunodeficiency, aspiration, structural abnormality, or CF/PCD
• Allergic Bronchopulmonary Aspergillosis (ABPA) — Corticosteroids; itraconazole and voriconazole; omalizumab for steroid-dependent ABPA
• Bronchiolitis Obliterans — Post-infectious and post-transplant BO; azithromycin; montelukast; systemic corticosteroids
• Tuberculosis — Standard and drug-resistant TB treatment; contact tracing and preventive therapy

Pulmonary Function & Diagnostic Laboratory

FUCH's pulmonary function laboratory provides the full range of respiratory diagnostic testing for children of all ages:

• Spirometry and bronchodilator reversibility testing
• Infant pulmonary function testing (raised volume rapid thoracic compression)
• Whole body plethysmography for lung volumes
• Diffusing capacity (DLCO) for ILD assessment
• Exhaled nitric oxide (FeNO) for eosinophilic airway inflammation
• Nasal nitric oxide for PCD screening
• Exercise challenge testing for exercise-induced bronchoconstriction
• Polysomnography for sleep-disordered breathing

Flexible Bronchoscopy Program

FUCH's bronchoscopy program offers the full range of diagnostic and therapeutic flexible bronchoscopy for children:

• Bronchoalveolar lavage (BAL) for infection and ILD diagnosis
• Endobronchial biopsy for airway pathology
• Transbronchial biopsy for ILD diagnosis
• Foreign body removal
• Airway assessment for tracheobronchomalacia and structural abnormalities

Why International Families Choose FUCH Pulmonology

• Severe Asthma Biologic Program — Mepolizumab, benralizumab, dupilumab, and tezepelumab for severe eosinophilic and allergic asthma
• chILD Expertise — Surfactant dysfunction disorders, NEHI, and other rare childhood ILDs with genetic diagnosis
• CFTR Modulator Access — Elexacaftor/tezacaftor/ivacaftor (Trikafta) for eligible CF patients
• PCD Diagnosis — Comprehensive PCD diagnostic program including nasal NO, electron microscopy, and genetic panel
• Sleep Medicine — Polysomnography and home ventilation for sleep-disordered breathing and hypoventilation syndromes
• Cost-Effectiveness — World-class pediatric pulmonology care at significantly lower cost than equivalent treatment in Western countries

The CMCS Patient Journey

1. Initial Inquiry — Share your child's respiratory history, pulmonary function tests, CT scans, bronchoscopy reports, genetic testing, and current medications with CMCS.
2. Medical Record Preparation — We translate and organize your child's records for specialist pre-consultation review.
3. Specialist Matching — We identify the most appropriate pediatric pulmonologist based on your child's condition — asthma, ILD, CF, PCD, bronchiectasis, or sleep-disordered breathing.
4. Priority Scheduling — We secure a consultation with minimal waiting time.
5. Travel & Logistics — Assistance with visa invitation letters, family accommodation near FUCH, and Shanghai airport transfers.
6. On-Site Concierge — Bilingual coordinators accompany your family throughout hospital visits, managing registration, translation, and communication.
7. Diagnostic Support — Full coordination of pulmonary function testing, bronchoscopy, CT, genetic testing, and sleep studies.
8. Post-Consultation Follow-Up — Test result translation, treatment plan interpretation, and remote follow-up coordination after you return home.

Book a Consultation

If your child has severe asthma, a rare interstitial lung disease, cystic fibrosis, primary ciliary dyskinesia, bronchiectasis, or a complex respiratory condition — CMCS can arrange a specialist consultation with FUCH's pediatric pulmonology team in Shanghai.

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